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Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive.

A genome engineering technique developed at UT Southwestern Medical Center helped make the institution a research partner in a new $185 million National Institutes of Health (NIH) initiative to build on findings of the Human Genome Project.

Using artificial intelligence (AI), researchers from UT Southwestern have developed a way to accurately predict which skin cancers are highly metastatic.

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

Jere Mitchell, M.D., former director of the Harry S. Moss Heart Center at UT Southwestern Medical Center and an internationally recognized exercise physiologist whose seminal findings on maximal oxygen uptake changed conventional medical practice on bed rest and laid the foundation for central command physiology, died July 17. He was 92.

The body’s ability to prevent food poisoning by producing a natural antimicrobial compound increases during the day, when exposure to noxious bacteria is most likely, a new study by UT Southwestern scientists suggests.

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration.

Adenomyosis – an abnormal tissue growth into the muscular wall of the uterus that causes painful cramps and heavy or prolonged menstrual bleeding – is more common than generally appreciated, a review of the literature by gynecologists at UT Southwestern Medical Center revealed.