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Staff Andy Lemoff, Ph.D. – Core Director Associate Professor, Department of Biochemistry Faculty Profile & Publications Room: Y4.310D Email: andrew.lemoff@utsouthwestern.edu Xuemei Luo, Ph.D. Instructor, Department of Biochemistry Room: Y4.306 Email: xuemei.luo@utsouthwestern.edu Joe Otto, Ph.D. Seni…

Instrumentation The core is equipped with seven mass-spectrometry platforms to provide a wide range of analyses to customers and collaborators. These instruments are housed in a purpose-built access-controlled facility with dedicated HVAC, and many power and network connections. This facility provide…

FAQs Q: Why are your services so expensive?! A: They aren’t! Our rates are comparable to, or cheaper than, the majority of other academic proteomics facilities. We will work hard to maximize our sample throughput, and automate our procedures, so that we do not have to raise prices. Proteomics is expe…

2019 Publications Bing C, Patel P, Staruch RM, Shaikh S, Nofiele J, Wodzak Staruch M, Szczepanski D, Williams NS , Laetsch T, Chopra R. Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal …

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

Formulation It is frequently necessary for most hydrophobic small molecules to develop a specific formulation that will allow in vivo delivery of the compound at suitable concentrations. The Pharmacology Core makes use of a simple decision tree published some years ago by scientists at Pfizer for dev…

Zeiss LSM880 Airyscan (K1.224) For conventional and superresolution confocal microscopy of immunofluorescent cell cultures and tissue sections. 405, 458, 488, 514, 561, and 633 nm laser lines 32-channel spectral detection Live cell incubation Airyscan FAST for up to 70% improved resolution in all dim…

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

Zeiss LSM880 Inverted (NL7.134A) Visible laser lines: 405, 458, 488, 514, 561, 594, and 633 nm for conventional confocal applications Spectral detection for optimized CFP/YFP FRET and spectral unmixing of closely overlapping fluorophores (e.g. GFP and YFP, multiplexed Qdots) Tunable NIR laser for mul…

Zeiss LSM980 Airyscan2 (NL5.120LA) For conventional and superresolution confocal microscopy of immunofluorescent cell cultures and tissue sections. 405, 445, 488, 514, 561, 594, 639 and 730nm laser lines AI sample finder for automatic sample detection and tiling Fast xy-stage for multi-point acquisit…