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Gao Lab creates nanoparticle to trigger STING pathway

UT Southwestern researchers have created a new nanoparticle-based drug capable of eradicating metastatic cancers in mouse models. Their study, published in Nature Nanotechnology, successfully targeted and treated multiple cancer foci by activating the STING pathway after intravenous injection of a nanoparticle that responds to two tumor-specific signals.


UTSW receives ARPA-H award to create functioning artificial liver

UT Southwestern Medical Center has received an award from the Advanced Research Projects Agency for Health (ARPA-H) to develop livers using patients’ own cells and an innovative three-dimensional (3D) printing approach. If successful, this project – known as Vascularized Immunocompetent Tissue as an Alternative Liver (VITAL) – could significantly reduce the gap between supply and demand for donor livers, negate the necessity of lifelong immunosuppression for liver transplant patients, and create artificial livers for in vitro drug testing and research.


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