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Deltavision Deconvolution Microscopes (K1.228, NL5.120R) Inverted wide-field epifluorescence microscopes engineered for high fidelity image acquisition from live or fixed samples up to 50 μm in thickness. Efficient constrained iterative deconvolution algorithm, high precision point-visiting stage for automated time-lapse imaging from multiple fields of view. Shuttered white-light excitation minimizes photobleaching and phototoxicity. 4, 10, 20, 40, 60 and 100x objectives, phase and DIC available

The Metabolomics Core Facility offers a variety of metabolomics services including targeted and untargeted metabolomics and more.

2019 Publications Bing C, Patel P, Staruch RM, Shaikh S, Nofiele J, Wodzak Staruch M, Szczepanski D, Williams NS , Laetsch T, Chopra R. Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal doxorubicin . Int J Hyperthermia . 2019;36(1):196-203. PMCID: PMC6430695. Lewis JE, Singh N, Holmila RJ, Sumer BD, Williams NS , Furdui CM, Kemp ML, Boothman DA. Targeting NAD+ Metabolism to Enhance

2020 Publications Cheng B, Bing C, Staruch RM, Shaikh S, Wodzak Staruch M, Szczepanski D, Williams NS , Laetsch TW, Chopra R. The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes . Int J Hyperthermia . 2020;37(1):1052-1059. PMCID: PMC7727403. Beattie SR, Schnicker NJ, Murante T, Kettimuthu K, Williams NS , Gakhar L, Krysan DJ. Benzothiourea Derivatives Target the

Caco-2 Permeability Caco-2 assays measure the ability of a drug to be absorbed from the gastrointestinal tract and thereby to evaluate whether the drug can be suitably dosed via an oral route. It also provides information regarding the ability of a compound to serve as a substrate for the P-glycoprotein (Pgp) efflux drug pump. Caco-2 cells are intestinal epithelial tumor cells that form a polarized monolayer, a well-defined brush border on the apical surface and intercellular junctions when

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

General and contact information about UT Southwestern's Institutional Animal Care and Use Committee (IACUC)

EPIC Care & MCSA

Data Management Our computers are not intended for storage, only for data acquisition, and we are not responsible for your data! Data must be backed up at the end of each session to a storage location managed by the user! To provide enough storage for new data, we reserve the right to delete older data from our computers without warning. The user data folders on all our computers are accessible via the campus LAN. Off-campus access to these computers requires a VPN connection ( VPN access ). To