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An Investigational New Drug (IND) is a request for authorization from the Food and Drug Administration (FDA) to administer an investigational drug or biological product to humans. Following preclinical benchwork, conducting investigations under an IND is the first step to getting a new drug approved

Publications Huang, W.; Li, H.; Kiselar, J.; Fink, S. P.; Regmi, S.; Day, A.; Yuan, Y.; Chance, M.; Ready, J. M.; Markowitz, S. D.; Taylor, D. J. Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system . Nature Commun . 2023, 14. Imlay, L. S.; Lawong, A. K.; Gahalawat, S.; Kumar, A.; Xing, C.; Mittal, N.; Wittlin, S.; Churchyard, A.; Niederstrasser, H.; Crespo-Fernandez, B.; Posner, B. A.; Gamo, F.-J.; Baum, J.; Winzeler, E. A.; Laleu, B.; Ready, J. M.; Phillips, M

Patents Issued Patents Markowitz, S.; Ho, W. J.; Yuan, Y.; Jain, M.; Sabeh, M.; Ready, J.; Williams, N. Inhibitors of short-chain dehydrogenase activity for treating coronary disorders. 2022, US 11,426,420 B2. Word, R. A.; Annavarapu, H. K.; Posner, B.; Ready, J.; Markowitz, S. Compositions and methods for modulating cervical ripening. 2019, WO 2019010482. Markowitz, S.; Antczak, M.; Ready, J.; Zhang, Y. Preparation of thienopyridines and related compounds, their compositions and methods of

Review pricing information for the Metabolomics Core Facility.

Hamid Baniasadi, Ph.D., is an Assistant Professor in the Department of Biochemistry at the University of Texas Southwestern Medical Center, as well as the Director of Metabolomics Core Facility within the Biochemistry Department.

16S Sequencing Assay Overview We provide services to sequence various hypervariable regions (V1-V9) of 16S rRNA gene for bacterial taxonomy and phylogeny. Customer can select the hypervariable region/s based on their sample source and study aims. A sketch of 16S rRNA gene and hypervariable regions. For commonly studied regions such as: V3 & V4, we use Illumina Nextera recommended primer sets and protocol to amplify the targeted region/s and ligate illumina adapter & barcodes. We also offer in

The Metabolomics Core Facility offers a variety of metabolomics services including targeted and untargeted metabolomics and more.

Find answers to common questions about the Metabolomics Core Facility.

Services 2025-2026 CMRU Physiology Lab Services Echo Services POC Limited Echo Clinical Echo 2D with Reading Clinical Echo 3D with Reading Stress Echo with Reading Clinical Echo 2D and Stress Test with Reading Additional Views/ Complex Caseload CPET Services Cardiopulmonary Exercise Testing (CPET) Additional Views/ Complex Caseload Combination Tests CPET + Stress Tests Additional Views/ Complex Caseload * Complex CPET and ultrasonography cases are carefully planned with the clinician–scientist

Find out how to prepare and submit samples to the Metabolomics Core Facility.