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Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

A set of interacting molecules in immune cells of the gut is responsible preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study.

With antibiotic-resistant bacteria on the rise, scientists have been searching for ways to shut down the Type IV secretion system (T4SS), a protein complex on the outer envelope of bacterial cells that helps them to exchange DNA with neighboring bacteria and resist antibiotics.

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals worldwide each year and kills hundreds of thousands.

UT Southwestern Medical Center has been selected as the nation’s first academic medical center to participate in the American Chemical Society (ACS) Bridge program, designed to increase the number of Black, Latino, and Indigenous students earning doctorates in chemistry.

UT Southwestern Medical Center scientists have identified the first two cases of the Beta variant (B.1.351) of COVID-19 infection in North Texas using next-generation sequencing technologies along with targeted PCR testing.

Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes – parasitic flatworms that cause the little-known tropical disease schistosomiasis.

Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based

Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires’ disease to set up house in the cells of humans and other hosts.