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The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical Center reported in a retrospective study.

A phase three clinical trial co-led by a researcher at UT Southwestern Harold C. Simmons Comprehensive Cancer Center showcases the promise of administering immunotherapy along with chemotherapy before surgery in patients with breast cancer at high risk of spreading. The findings, published in Nature

As weight-loss drugs capture the public’s imagination, UTSW and its Nutrition Obesity Research Center are uniquely positioned to lead the way in discovery, education, and community outreach.

UT Southwestern Medical Center’s Center for Depression Research and Clinical Care is collaborating with mental health colleagues across the country to expand detection and treatment for depression and other disorders across Texas as part of the Lone Star Depression Challenge.

A growing number of U.S. adults consider electronic cigarettes (e-cigarettes) more harmful than conventional cigarettes, UT Southwestern Medical Center researchers show in a study.

Stories published in 2023 about UT Southwestern Medical Center.

Jean D. Wilson, M.D., an internationally known endocrinologist whose scientific discoveries led to profound insights into the mechanisms underlying sexual differentiation and led to now widely used treatments for prostate disease, died June 13. He was 88.

Maralice Conacci-Sorrell, Ph.D., Associate Professor of Cell Biology at UT Southwestern Medical Center, is the recipient of the 2026 Mary Beth Maddox Award and Lectureship from the Texas Academy of Medicine, Engineering, Science & Technology (TAMEST).

A newly discovered “timekeeper” for fighting infections dramatically shapes the body’s immune defenses.

Stories published in 2024 about UT Southwestern Medical Center.