UT Southwestern Medical Center scientists have identified a gene that appears to act as a master control switch for reactive gliosis, a prominent feature of many neurodegenerative diseases that is thought to contribute to their pathology.

Total knee replacements performed with the help of a surgical robot have better outcomes on average than similar surgeries performed manually but can cost significantly more, a new study by UT Southwestern Medical Center researchers shows.

Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer’s, Huntington’s, and Parkinson’s.

Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.

More than a dozen UT Southwestern Medical Center scientists are included on the 2023 Highly Cited Researchers list, which recognizes the top 1% of researchers from around the world who have demonstrated significant and broad influence in their chosen field or fields of research.

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

A gene that’s well known for its role in turning on tumor-suppressing genes when cells become stressed also keeps potential tumor-driving genes turned off, UT Southwestern researchers report in a new study.

UT Southwestern Medical Center is expanding an evidence-based mental health promotion and crisis prevention program for adolescents to schools across Texas after receiving $11.5 million in funding from the state.

Patients with inflammatory bowel disease (IBD) who required treatment with biologic therapies and were enrolled in a financial assistance program were less likely to need surgery after starting medication than those not enrolled in a program, a study by UT Southwestern researchers found.

An innovative virtual reality (VR) training tool could soon play a major role in helping physicians recognize and respond to potentially violent patient encounters.