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Diabetes drug metformin may protect against radiation exposure: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/aug-diabetes-drug-metformin.html

Metformin, a well-tolerated diabetes drug prescribed to as many as 150 million people worldwide, may also protect cells from radioactive damage, UT Southwestern Medical Center researchers report.

Supplement lowers risk of higher glucose caused by blood-pressure drug: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/nov-blood-pressure-drug.html

A dietary supplement developed by a UT Southwestern Medical Center researcher significantly reduced high blood sugar caused by a diuretic used to lower blood pressure while also correcting electrolyte imbalances, UTSW researchers report.

Lots of water, small dietary changes can help prevent kidney stones, UTSW expert says: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-prevent-kidney-stones.html

The painful experience of having a kidney stone has become more common in recent years, including in Texas, part of the “Stone Belt” where hot weather can cause dehydration. But small dietary changes as well as drinking lots of water can help avert the discomfort, says a board-certified physician

Video helps defibrillator patients make informed choices : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-video-defibrillator-patients.html

A UT Southwestern Medical Center quality improvement team led a large-scale, multispecialty project in partnership with the Parkland Center of Innovation and Value to help patients with implantable cardioverter defibrillators (ICDs) better understand their devices and make choices about their care.

Gene-editing nanoparticles correct stem cell mutations in cystic fibrosis models : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/june-gene-editing-nanoparticles.html

Researchers at UT Southwestern Medical Center developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis (CF), swapping a mutated form for a healthy one that persisted in stem cells. Their findings, reported in Science, could offer hope

UT Southwestern collaborates with Pfizer to develop improved RNA delivery technologies: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/feb-pfizer-rna-technologies.html

UT Southwestern Medical Center is collaborating with Pfizer Inc. to develop RNA enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center’s Program in Genetic Drug Engineering.

Neurostimulation shows promise as potential Alzheimer’s treatment : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-neurostimulation-alzheimers-treatment.html

Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of

Why do women have more trouble after knee injuries? UTSW model explains: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-women-knee-injuries.html

A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds light on why women tend to have worse outcomes after knee injuries than men. Their findings, published in Scientific Reports, could facilitate research into new therapies for

Stimulating fat cells with GIP receptor has potential to treat obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-fat-cells-with-incretin.html

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

Autoimmune skin condition linked to higher risk of heart disease: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-autoimmune-skin-condition.html

Patients with cutaneous lupus erythematosus (CLE), an autoimmune disease that causes skin inflammation, have a higher risk for atherosclerotic cardiovascular disease (ASCVD), or hardening of the arteries, UT Southwestern Medical Center researchers found.