Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

UT Southwestern is joining with medical centers around the nation to apply advanced sequencing to pediatric brain tumors as part of the National Cancer Institute’s new Molecular Characterization Initiative, a subset of the Cancer Moonshot Childhood Cancer Initiative.

UT Southwestern Medical Center scientists have identified the first two cases of the B.1.617.2 (Indian origin) variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with targeted PCR testing.

A subtle smile emerged on Dr. James Leidner’s face as he envisioned telling people of the unusual contribution he made to mankind’s mission to Mars.

Forbes and Statista have selected UT Southwestern among the top 40 Best Employers for Women 2021.

An international panel of experts from four renowned diabetes research centers, including UT Southwestern Medical Center, has reviewed current literature and is recommending a pivotal change in treatment of Type 2 diabetes to focus on obesity first and glucose control second.

Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

A new “self-driving” microscope developed by UT Southwestern Medical Center researchers solves two fundamental challenges that have long plagued microscopy: first, imaging living cells or organisms at dramatically different scales, and second, following a specific structure or area of interest over

Transfer RNA (tRNA), a genetic molecule well known for its contribution in reading the instructions for building proteins, is also key in regulating how long those instructions persist in cells, a new study by UT Southwestern Medical Center researchers shows.

World health experts have long suspected that the incidence of COVID-19 has been higher than reported.