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Children’s Research Institute at UT Southwestern scientists identify feature of aggressive non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-cri-utsw-aggressive-non-small-cell-lung-cancer.html
In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center
Repurposed drug has promising efficacy in non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-efficacy-non-small-cell-lung-cancer.html
An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in non-small cell lung cancer (NSCLC) with KRAS mutations, a clinical trial led by UT Southwestern Harold C. Simmons Comprehensive Cancer Center researchers showed.
Findings may move science closer to growing organs in other species: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-growing-organs-other-species.html
Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.
Gene that regulates immune activity in the retina identified: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2023/july-gene-that-regulates-immune-activity.html
UT Southwestern Medical Center researchers have identified a gene called Lipe that appears to be pivotal to retinal health, with mutations spurring immune activation and retinal degeneration. This is important because the retina is responsible for detecting the light that is transformed into vision.
CRI scientists discover metabolic feature that allows melanoma cells to spread : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2019/metabolic-feature-melanoma-cells-spread.html
Researchers at Children’s Medical Center Research Institute at UT Southwestern (CRI) have uncovered why certain melanoma cells are more likely to spread through the body.
Dallas Mavericks and UT Southwestern strengthen strategic partnership : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-dallas-mavericks-utsw-partnership.html
Today the Dallas Mavericks and UT Southwestern Medical Center announced a multiyear expansion of their strategic partnership. UT Southwestern, the team’s Official Health Care Partner since 2019, will now also serve as the Official Team Doctors for the franchise. The UT Southwestern logo will appear
Online discrimination fuels drinking by Hispanic college students: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-online-discrimination-hispanic-college-students.html
Hispanic college students who encounter racial or ethnic discrimination on social media are more likely to turn to alcohol as a coping mechanism, according to a study led by a UT Southwestern Medical Center researcher.
Targeted therapy helps NICU parents reframe fears
https://www.utsouthwestern.edu/newsroom/articles/year-2025/sept-targeted-therapy-helps-nicu-parents.html
A cognitive behavioral therapy (CBT) program developed for parents whose child was born prematurely reduced harmful perceptions that their child remained medically fragile, according to a new study led by UT Southwestern Medical Center.
Protein pivotal for B-cell cancers gets a closer look: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-protein-pivotal-b-cell-cancers.html
Using a cutting-edge imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that’s crucial to the survival of malignant cells in some leukemias, lymphomas, and multiple myelomas.
Electrical stimulation offers hope for treating spinal injuries : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/may-electrical-stimulation-spinal-injuries.html
A grid of electrodes placed on the backs of study participants delivered enough low-voltage electrical stimulation through the skin to change the short-term function of spinal cord neurons, a study led by UT Southwestern Medical Center researchers showed.