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COVID-19 patient outcomes affected by cardiovascular risk : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/covid-19-patient-outcomes-affected-by-cardiovascular-risk.html

Research presented today by UT Southwestern cardiologists at the annual American Heart Association (AHA) Scientific Sessions 2020 showed that Black and Hispanic people were more likely to be hospitalized with COVID-19 than white patients, and that nonwhite men with cardiovascular disease or risk factors were more likely to die.

Study details how general anesthetics and 'benzos' act on receptors in the brain: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/how-general-anesthetics-and-benzos-act-on-receptors.html

As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor.

Immunotherapy side effect could be a positive sign for kidney cancer patients : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/immunotherapy-side-effect-could-be-a-positive-sign.html

An autoimmune side effect of immune checkpoint inhibitor (ICI) drugs could signal improved control of kidney cancer, according to a new study by researchers in UT Southwestern’s Kidney Cancer Program (KCP).

Development of new stem cell type may lead to advances in regenerative medicine: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/new-stem-cell-regenerative-medicine.html

A team led by UT Southwestern has derived a new “intermediate” embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.

Cancer metabolism researcher Ralph DeBerardinis elected to the National Academy of Medicine : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/ralph-deberardinis-elected-to-the-national-academy-of-medicine.html

Ralph DeBerardinis, M.D., Ph.D., a professor at the Children’s Medical Center Research Institute at UT Southwestern (CRI), has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.

High-sugar diet can damage the gut, intensifying risk for colitis : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/high-sugar-diet-can-damage-the-gut.html

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut’s protective mucus layer.

Breaking it down: How cells degrade unwanted microRNAs : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/how-cells-degrade-unwanted-micrornas.html

UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.

Cancer-fighting gene restrains 'jumping genes' : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/cancer-fighting-gene-restrains-jumping-genes.html

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or “jumping genes,” from hopping around the human genome.

UTSW performs first HIV-positive-to-HIV-positive organ transplant in Texas: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/hiv-positive-to-hiv-positive-organ-transplant.html

Less than three weeks after getting on an organ transplant list for HIV-positive patients, John Welch got the call. A liver was available from a deceased donor, and it was an excellent match.

Study explores why fasting can lead to a longer lifespan: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2026/april-fasting-and-refeeding-longer-lifespan.html

Restricting calories has long been recognized as a powerful way to live longer, with periods of intermittent fasting proving more effective than a steady diet. However, the mechanism behind this phenomenon has been unclear.