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2023 Publications for the Preclinical Pharmacology Core Lab at UT Southwestern

2022 Publications for the Preclinical Pharmacology Core Lab at UT Southwestern

Cytochrome P450 Inhibition Currently under Redevelopment Because of the important role of Cytochrome p450 enzymes in drug metabolism, it is important to assess the ability of lead compounds to inhibit specific cytochrome p450 enzymes to avoid potential drug-drug interactions where one drug may affect…

Acknowledgment For the QLMC, it is of utmost importance that you inform us of, and acknowledge the QLMC in, any publications containing data (images and/or quantification) acquired on our microscopes or with our help. This is the most important metric various funding sources consider for supporting n…

Core rates UT Southwestern Core Facility Rates Current cost recovery rates in UT Southwestern core laboratories are set by the Dean’s office at ~60% and do not recoup costs associated with the purchase of new equipment by individual facilities. Charges to UT Southwestern investigators are based on th…

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STED (access provided through the Peter O'Donnell Jr. Brain Institute) This system is owned by the Peter O'Donnell Jr. Brain Institute. The Abberior Facility Line system is a cutting-edge, high-end 3-D STED super-resolution imaging system capable of providing 40 nm isotropic resolution in samples up …

2021 Publications Li J, Canseco D, Wang Y, Vale G, Chaudhary J, Anwar A, Baniasadi H, Williams NS , Gopal P, Sutphin PD, McDonald JG, Putnam WC, Corbin IR. Assessing the safety of transarterial locoregional delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat liver. Eur J…

Zeiss LSM780 Upright (ND5.740) Upright confocal microscope configured for organ culture and whole animal imaging Visible laser lines 405, 458, 488, 514, 561, 594, 633 nm. Coherent Vision II laser for two-photon imaging and SHG Spectral detection with ultrasensitive GaAsP detector Two non-descanned de…

Cancellation/No-show Due to the heavy use of our microscopes, we require that if you have to cancel your session, you do so at least 12 hours before the scheduled start time. If you cannot connect to the scheduler or are within the 12-hour time window, please QLMC@utsouthwestern.edu . Failure to canc…