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UT Southwestern Medical Center has been recognized for its decades of commitment to developing female leaders in medicine and science and its far-reaching impact in supporting and advancing women’s careers.

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children’s Medical Center Research Institute at UT Southwestern published in Cell.

Transfer RNA (tRNA), a genetic molecule well known for its contribution in reading the instructions for building proteins, is also key in regulating how long those instructions persist in cells, a new study by UT Southwestern Medical Center researchers shows.

To meet the growing demands for cancer treatment in Tarrant County and surrounding areas, UT Southwestern Medical Center is expanding its cancer services in the Fort Worth Medical District with construction of a new two-story Radiation Oncology campus that will house the city’s first MRI-guided precision radiation treatment.

An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in non-small cell lung cancer (NSCLC) with KRAS mutations, a clinical trial led by UT Southwestern Harold C. Simmons Comprehensive Cancer Center researchers showed.

In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cancer Discovery, tumors with this metabolic activity result in early patient death.

Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers.

With knee replacement surgery becoming more common, Varatharaj Mounasamy, M.D., Professor of Orthopaedic Surgery at UT Southwestern Medical Center who specializes in hip and knee replacements, recommends taking off from work for a few weeks, joining a class to learn more about joint replacement, and attending physical therapy before surgery.

More clinical research is needed to investigate how reducing alcohol consumption in patients with alcohol-related liver disease (ALD) may slow disease progression and improve outcomes, according to an international task force of experts from more than two dozen institutions including UT Southwestern Medical Center.

Researchers at UT Southwestern Medical Center are part of a team that developed a simple blood test that can detect developing heterotopic ossification (HO), the abnormal formation of bone in soft tissues after injury or surgery, weeks before it can be identified by traditional imaging.