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UT Southwestern Medical Center researchers have identified hundreds of genomic variants associated with autism spectrum disorder (ASD) in East African families who have a markedly higher prevalence of the neurodevelopmental condition than other areas worldwide.

Mitochondria that power cellular activity fragment and change shape in breast cancer cells that migrate to the brain, an adaptation that appears necessary for the cells to survive, UT Southwestern Medical Center researchers report in a new study. The findings, published in Nature Cancer, could lead to new ways to prevent brain metastases, or the spread of cells from primary tumors to the brain.

If you’re feeling tired this coming week, don’t be surprised. Moving our clocks ahead one hour to shift into daylight saving time (which occurs at 2 a.m. Sunday) disrupts the body’s biological clock, affecting sleep patterns and how we function, according to a UT Southwestern Medical Center neuroscientist who researches circadian rhythms.

Patients with sickle cell disease (SCD) who undergo total knee replacement are at higher risk for complications than non-SCD patients, according to a large-scale, retrospective study by researchers from UT Southwestern Medical Center and the University of Calgary.

It’s almost that dreaded time of year, when spring and summer allergies can make life miserable for many.

A clinical trial led by UT Southwestern Medical Center researchers demonstrates that providing healthy food directly to patients recovering from heart failure is feasible and well accepted – and could improve quality of life – helping build a foundation for larger studies exploring food as a component of medical care.

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.

UT Southwestern Medical Center researchers have identified an experimental molecular compound that significantly improved survival among cellular models and mouse models of amyotrophic lateral sclerosis (ALS), the fatal neurodegenerative disease.

By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.