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– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues.

Patients considering LASIK vision correction surgery should consider the risks as well as benefits and see a doctor who can assess whether they are a good candidate for the procedure, according to an ophthalmologist at UT Southwestern Medical Center.

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that’s critical for successful viral replication.

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.

Maternal anemia has the same definition across the sociodemographic spectrum, according to a UT Southwestern study of a diverse population of uncomplicated patients.

Researchers at UT Southwestern Medical Center studied obstructive sleep apnea in a large group of children and concluded that underweight children with this condition are more likely to have decreased height, tonsillar hypertrophy, and allergic rhinitis.

An analysis of more than 400 singers who sought treatment at UT Southwestern Medical Center for vocal injuries provides a wealth of data on a topic that’s often considered taboo to discuss in the singing community.

A new approach that targets the cellular machinery that viruses need to reproduce – rather than the virus itself – appears to stem replication of a common childhood pathogen known as respiratory syncytial virus (RSV), UT Southwestern researchers report in a new study.