The Cancer Cell Imaging Core (CCIC) streamlines the imaging pipeline with fully automated operations, enabling researchers to visualize cancer processes with unprecedented resolution.
Technology that Empowers Research
CCIC provides high-resolution 3D light-sheet imaging of cancer in tissue contexts, delivering multiscale, multiplexed data and quantitative analysis powered by high-performance computing. We enable in situ visualization of cell states and interactions across multiple scales—from whole tissues to subcellular resolution.
CCIC streamlines:
- Antibody validation
- Tissue clearing
- Expansion microscopy
- Cyclic multiplexed imaging
- Live imaging of spheroids
Fully automated operations are supported by robotics and high-performance computing.
By integrating spatially resolved transcriptional and metabolic data with quantitative imaging, and providing access to powerful, cloud-based analysis tools via a user-friendly web interface, CCIC empowers researchers to uncover the functional impact of oncogenic processes in realistic tissue environments.
Supporting Cutting-Edge Research
Operating on a fee-for-service model with robust training and support, CCIC facilitates cutting-edge cancer research across UT Southwestern and partnering institutions in Texas through scalable, standardized, and reproducible imaging pipelines that are unique in the field.
CCIC imaging services combine:
- State-of-the-art multiscale imaging
- Tissue clearing
- Thick-tissue cyclic immunofluorescence
- Expansion microscopy
- Tailored image analysis
We primarily serve our UTSW research community, however, CCIC will also collaborate with other institutions state-wide.