ADAPT-2 Study

ADAPT-2 (Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use Disorder)

We are looking for adults (18-65 years of age) who are using methamphetamine and are interested in reducing or stopping their meth use. There are no approved treatments specifically for methamphetamine use disorder. The CTN Texas Node is leading a groundbreaking study to test a combination of medications as a possible treatment for methamphetamine use disorder. A smaller pilot study (called ADAPT) showed a certain combination of medications may help people reduce their methamphetamine use. We are now testing the same combination of medications in a larger study that we call ADAPT-2.  

All eligible participants will be randomly assigned to receive a combination of two medications. Some people will receive medications with active ingredients and some will receive medications with inactive ingredients (known as placebo). No one (not the participants or the researchers) will know or can control which medications go to which participants. This is the best way to know whether or not this medication is helpful. Study medications and assessments will be provided to participants at no cost. Participants will receive compensation for their time and efforts. Eligible participants are expected to attend visits two times a week for 12 weeks. Study participation is completely voluntary.

Study information will be kept strictly confidential. Your privacy is important to us.

Call us for more information at (214) 648-8810