Clinical Researchers
Center for Depression Research and Clinical Care
Research focusing on pediatric populations with depressive disorders
Brown Lab: Psychoneuroendocrine Research Program
Psychoneuroendocrine research program focusing on substance abuse, dual diagnoses, and effects of corticosteroids on mood and memory
Coughlin Lab: Brain Health Program
Brain Health Program researching molecular neuroimaging techniques, particularly the use of novel radiotracers with positron emission tomography
Texas Alzheimer’s Research and Care Consortium
Investigating short- and long-term effects of concussion and early detection and differential diagnosis of neurodegenerative conditions of aging
Combining tools from cognitive neuroscience, psychiatry & developmental psychology to elucidate the brain circuits and mechanisms supporting language & cognition in humans
Pediatric Behavioral Health Research
Studying adolescent suicide prevention and treatment for suicidal adolescents
Developing analytical methods to integrate microbiome data with neuroimaging, behavioural, and clinical data sets to better understand the individual nature of microbiome-host interactions in health and disease
Community-Based Peer-Delivery Recovery Education
Researching health disparities with a focus on recovery within the field of mental health
Schizophrenia/Tamminga Research Lab
Investigating neurobiological mechanisms of schizophrenia and related disorders and developing human in vivo biomarkers for psychotic disorders, primarily using cognition and multimodal brain imaging measures
Jarrett Lab: Psychosocial Research
Evaluating the role of psychosocial factors and interventions on the course of health in mood and related disorders
Clinical Neuroscience Scholars Program
Researching biomarkers to predict post-surgery outcomes for patients with intractable epilepsy with the aim of guiding patient discussions on prognosis, treatment, and managements
LoBue Lab: Brain Aging, Injury, and Modulation
Brain aging, injury, and modulation: investigating later-in-life effects of traumatic brain injury and studying effects of noninvasive brain stimulation in Alzheimer’s disease and related disorders
Focusing on functional neuro-imaging studies to examine the connection between biological, psychological, and social aspects of eating disorders
Interventional Psychiatry Research Program
Furthering the development and utility of neurotherapeutic interventions for use in scientific investigations and clinical practice
North Texas Burn Rehabilitation Model System
Focusing on strategies for improving suicide risk detection in health care systems and psychological recovery after traumatic injury, particularly among survivors of major burn injuries
Focusing on improving cognition in older adults with or at risk for dementia through brain stimulation, with cognitive, functional, and pharmacological modalities
Schizophrenia/Tamminga Research Lab
Investigating the nature and treatment of cognitive deficits commonly seen in schizophrenia and related disorders
Establishing antidepressant treatment efficacy, examining treatment-resistant depression to develop algorithms and guidelines, developing and validating biomarkers to reach the goal of precision medicine for mood disorders
- Our Recent Publications
Polygenic Risk Score Analysis of Antidepressant Treatment Outcomes: A CAN-BIND-1 Study Report: Analyse des résultats du traitement antidépresseur à l'aide des scores de risque polygéniques: Rapport sur l'étude CAN-BIND-1.
Magarbeh L, Elsheikh SSM, Islam F, Marshe VS, Men X, Tavakoli E, Kronenbuerger M, Kloiber S, Frey BN, Milev R, Soares CN, Parikh SV, Placenza F, Hassel S, Taylor VH, Leri F, Blier P, Uher R, Farzan F, Lam RW, Turecki G, Foster JA, et al.
Can J Psychiatry. 2025 Mar 29:7067437251329073.Should Inflammation Be a Specifier for Major Depression in the DSM-6?
Jha MK, Leboyer M, Pariante CM, Miller AH.
JAMA Psychiatry. 2025 Apr 2. doi: 10.1001/jamapsychiatry.2025.0206.Inclusivity in Epilepsy Care: Navigating the Complex Nature of Seizure Disorders in People Undergoing Gender-Affirming Care.
Alick-Lindstrom S, Weingarten MM, Falco-Walter JJ, Gidal BE, Abramowitz J, Lane CE, et al.
Epilepsy Curr. 2025 Mar 2:15357597251317908.White Matter, Cognition, and Electrophysiological Variables in Bipolar Disorder: Using Multimodal Integration of Biomarker Variables Associated With Bipolar Disorder to Elucidate Deficits.
Berardi A, Brown JA, Jackson BS, Huang LY, Trotti RL, Parker DA, Hill SK, Ivleva E, Pearlson GD, Tamminga CA, et al.
Bipolar Disord. 2025 Mar 14. doi: 10.1111/bdi.70010.Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases.
Sanchez E, Coughlan GT, Wilkinson T, Ramirez J, Mirza SS, Baril AA, Dilliott AA, Frank A, Lang AE, Hassan A, Pollock BG, Scott CJM, Marras C, Fischer CE, Seitz D, Andriuta D, Dowlatshahi D, Grimes DA, Tang-Wai DF, Sahlas DJ, Rogaeva EA, Finger E, Robinson JF, Tan K, Binns MA, Tartaglia MC, Borrie MJ, Strong MJ, Ozzoude M, Nanayakkara ND, Goncalves RA, Bartha R, Hegele RA, Farhan SMK, Black SE, Kumar S, Symons SP, Haddad SMH, Pasternak SH, Arnott SR, Rajji TK, et al.
Neurology. 2025;104(7):e213438.Examining Treatment Options in Youth With Major Depressive Disorder: Observations From the TX‐YDSRN Registry Study.
Ayvaci ER, Nandy K, Becker R, Stone L, Minhajuddin A, Slater H, Goodman LC, Wakefield SM, Storch EA, Blader JC, Soutullo CA, Emslie GJ, Trivedi MH.
Psychiatric Research and Clinical Practice. 2025. doi:10.1176/appi.prcp.20240117Identifying causal neural oscillations underlying working memory.
Mirjalili M, Zomorrodi R, Daskalakis ZJ, Blumberger DM, Hill SL, Rajji TK.
Cereb Cortex. 2025;35(2):bhae492.Cognitive remediation for patients with late-life schizophrenia: A follow-up pilot study.
Golas AC, Elgallab BM, Abdool PS, Bowie CR, Rajji TK.
Int Psychogeriatr. 2025;37(2):100006.The Impact of Body Image on Physical Function and Return to Work After Burn: A Burn Model System Study.
Ali M, McMullen K, Solis-Beach K, Roaten K, et al.
J Burn Care Res. 2025;46(2):419-24.Systematic Review and Meta-Analysis: The Association Between Newer-Generation Antidepressants and Insomnia in Children and Adolescents With Major Depressive Disorder.
Türkmen C, Machunze N, Lee AM, Bougelet E, Ludin NM, de Cates AN, Vollstädt-Klein S, Bach P, Kiefer F, Burdzovic Andreas J, Kamphuis J, Schoevers RA, Emslie GJ, et al.
J Am Acad Child Adolesc Psychiatry. 2025 Jan 17:S0890-8567(25)00013-9.Symptom presentation and neurocognitive performance following sport-related concussion in adolescents with and without ADHD.
Allen TT, Bunt S, Hicks C, Didehbani N, Shurtz L, Silver CH, Cullum CM.
Child Neuropsychol. 2025. doi: 10.1080/09297049.2025.2465517.Traumatic Brain Injury and Risk of Incident Dementia: Forensic Applications of Current Research.
Clem MA, LoBue C, Schaffert J, Cullum CM.
Arch Clin Neuropsychol. 2025;40(2):289-301.Problematic social media use and relationship to mental health characteristics in youth from the Texas Youth Depression and Suicide Research Network (TX-YDSRN).
Kennard BD, Hughes JL, Minhajuddin A, Jones SM, Jha MK, Slater H, Mayes TL, Storch EA, LaGrone JM, Martin SL, Hamilton JL, Wildman R, Pitts S, Blader JC, Upshaw BM, Garcia EK, Wakefield SM, Trivedi MH.
J Affect Disord. 2025;374:128-40.Psychological interventions for preventing relapse in individuals with partial remission of depression: a systematic review and individual participant data meta-analysis.
Gülpen J, Breedvelt JJF, van Dis EAM, Geurtsen GJ, Warren FC, van Heeringen C, Hitchcock C, Holländare F, Huijbers MJ, Jarrett RB, et al.
Psychol Med. 2025;55:e50.Characteristics of patients with major depressive disorder eligible for and prescribed esketamine, treatment outcomes and physician experiences: a physician and patient survey in the United States.
Jha M, et al.
Curr Med Res Opin. 2025;41(2):355-68.Pharmacological reduction of reverse-translated hippocampal hyperactivity in mouse: relevance for psychosis.
Dybowski FP, Scott DS, Tamminga CA.
Neuropsychopharmacology. 2025. doi: 10.1038/s41386-025-02077-4.Advancing precision psychiatry and targeted treatments: Insights from immunopsychiatry.
Miller AH, Berk M, Bloch G, Briquet-Laugier V, Brouillon C, Cuthbert BN, Dantzer R, Davis MC, De Picker LJ, Drevets WC, Eyre HA, Hack LM, Harrison NA, Krystal AD, Lombardo G, Mondelli V, Pariante CM, Pulvirenti L, Salvadore G, Sforzini L, Swieboda P, Trivedi MH, et al.
Brain Behav Immun. 2025;125:319-29.Comparing the Neurocognitive Effects of Right Unilateral Ultra-Brief Pulse Electroconvulsive Therapy and Magnetic Seizure Therapy for the Treatment of Major Depressive Episode.
McClintock SM, Deng ZD, Husain MM, Thakkar VJ, Bernhardt E, Weiner RD, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging. 2025;10(2):175-85.Psychometric properties of the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) in adolescent and young adult psychiatric outpatients in the Texas Youth Depression and Suicide Research Network (TX-YDSRN).
Jeevarajan JR, Theodorou A, Nandy K, Guerra M, Madia ND, Claassen C, Goodman LC, Farmer D, Wakefield SM, Minhajuddin A, Slater H, Mayes T, Soutullo CA, Rosenberg A, Ladd S, Ahumada N, Jackson S, Rush AJ, Trivedi MH.
J Affect Disord. 2025;375:155-64.Endophenotype presentation of athletes with concussion contingent on sex and time since injury.
Beitchman JA, Chung JS, Jones JC, Hynan LS, Didehbani N, Cullum CM, et al.
Brain Inj. 2025. doi: 10.1080/02699052.2025.2449934.Clinical characterization and differentiation of B-SNIP psychosis Biotypes: Algorithmic Diagnostics for Efficient Prescription of Treatments (ADEPT)-1.
Clementz BA, Chattopadhyay I, Trotti RL, Parker DA, Gershon ES, Hill SK, Ivleva EI, Keedy SK, Keshavan MS, McDowell JE, Pearlson GD, Tamminga CA, et al.
Schizophr Res. 2023;260:143-51.Economic and clinical burden of major depressive disorder with insomnia symptoms in commercially and Medicaid-insured adults in the United States: A retrospective matched cohort study.
Kale H, Zhdanava M, Pilon D, Sheehan J, Drissen T, Boonmak P, Choudhry Z, Shah A, Jha MK.
J Affect Disord. 2025;372:653-64.Homocysteine, neurodegenerative biomarkers, and APOE ε4 in neurodegenerative diseases.
Lin WZ, Yu D, Xiong LY, Zebarth J, Wang R, Fischer CE, Rajji TK, et al.
Alzheimers Dement. 2025;21(1):e14376.Assessing plasticity in the primary sensory cortex and its relation with atypical tactile reactivity in autism: A TMS-EEG protocol.
Kariminezhad S, Zomorrodi R, Zrenner C, Blumberger DM, Ameis SH, Lin HY, Lai MC, Rajji TK, et al.
PLoS One. 2024;19(11):e0305013.Lived Experience and Family Engagement in Mental Health and Substance use Health Research: Case Profiles of Five Studies.
Hawke LD, Quilty L, Agic B, Courtney DB, Liddell G, Sibille E, Jennings S, Orson J, Harris H, McKee S, Sullivan C, Soklaridis S, Rajji TK, et al.
Health Expect. 2024;27(6):e70087.Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo.
Fu CHY, Antoniades M, Erus G, Garcia JA, Fan Y, Arnone D, Arnott SR, Chen T, Choi KS, Fatt CC, et al.
Nat Ment Health. 2024;2(2):164-76.An individual participant data meta-analysis of psychological interventions for preventing depression relapse.
Breedvelt JJF, Karyotaki E, Warren FC, Brouwer ME, Jermann F, Hollandare F, Klein N, de Jonge M, Klein DN, Farb N, Segal Z, Biesheuvel Leliefeld KEM, Jarrett R, et al.
Nat Mental Health. 2024;2:154–63.Genetic analysis of psychosis Biotypes: shared Ancestry-adjusted polygenic risk and unique genomic associations.
Xia C, Alliey-Rodriguez N, Tamminga CA, Keshavan MS, Pearlson GD, Keedy SK, Clementz B, McDowell JE, Parker D, Lencer R, Hill SK, Bishop JR, Ivleva EI, et al.
Mol Psychiatry. 2024. doi: 10.1038/s41380-024-02876-z.Race/ethnicity, sex, and age differences in pediatric SCAT-5 concussion symptoms.
Bunt SC, Silver CH, Shurtz L, Allen TT, Didehbani N, Hicks C, Chowdhury S, Wilmoth K, Hynan LS, Stokes M, Miller SM, Bell K, Cullum CM.
Appl Neuropsychol Child. 2024. doi: 10.1080/21622965.2024.2441490.Relationship between self-reported concussion history, cognition, and mood among former collegiate athletes.
Datoc A, Sanders GD, Tarkenton Allen T, Schaffert J, Didehbani N, Cullum CM.
Clin Neuropsychol. 2024. doi: 10.1080/13854046.2024.2440113.Neuronal viability/astrocyte activity ratio in the dorsolateral prefrontal cortex as a biomarker of Alzheimer's dementia: a proton magnetic resonance spectroscopy study.
Jha S, Torres-Carmona E, Iwata Y, Ma C, Graff-Guerrero A, Fischer CE, Mulsant B, Pollock BG, Rajji TK, et al.
Cereb Cortex. 2024;34(11):bhae465.Problematic Substance Use in Depressed Youth: Associations with Suicidal Ideation and Suicide Attempt History
Armstrong GM, Anderberg JL, Gorman AR, Spencer SD, Minhajuddin A, Ecker AH, Spofford J, Guzick AG, Slater H, Aloor FZ, Flores AM, Lagrone JM, Marino EN, Soutullo CA, Wakefield SM, Goodman WK Trivedi MH et al.
J Dual Diagn. 2024. doi: 10.1080/15504263.2024.2434219.Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial
Rajji TK, et al.
JAMA Psychiatry. 2024 Oct 30:e243241. doi: 10.1001/jamapsychiatry.2024.3241.The relationship between asthma and suggested alcohol dependence and heavy alcohol use in the Cooper Center longitudinal study: The role of depressive symptom severity
Agarwal CD, Shuval K, Li Q, DeFina LF, Barlow CE, Khan DA, Brown ES.
J Affect Disord. 2024;370:356-61.First responders have it covered
Green M, Foster JA.
Science. 2024;386(6721):497-98.Concurrent and prospective prediction of community-dwelling adults' psychosocial functioning with the Inventory of Depression and Anxiety Symptoms-II (IDAS-II)
Vittengl JR, Ro E, Jarrett RB, et al.
Psychol Assess. 2024. doi: 10.1037/pas0001347.Modulation of neural oscillations in escitalopram treatment: a Canadian biomarker integration network in depression study.
Schwartzmann B, Chatterjee R, Vaghei Y, Quilty LC, Allen TA, Arnott SR, Atluri S, Blier P, Dhami P, Foster JA, et al.
Transl Psychiatry. 2024;14(1):432.Endocannabinoid concentrations in major depression: effects of childhood maltreatment and relation to hippocampal volume
Mazurka R, Harkness KL, Hassel S, Stensson N, Nogovitsyn N, Poppenk J, Foster JA, et al.
Transl Psychiatry. 2024;14(1):431.Microbes and mood: innovative biomarker approaches in depression
Green M, Trivedi MH, Foster JA.
Trends Mol Med. 2024 Sep 30:S1471-4914(24)00241-7. doi: 10.1016/j.molmed.2024.09.002.Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration
Kiebs M, Farrar DC, Yrondi A, Cardoner N, Tuovinen N, Redlich R, Dannlowski U, Soriano-Mas C, Dols A, Takamiya A, Tendolkar I, Narr KL, Espinoza R, Laroy M, van Eijndhoven P, Verwijk E, van Waarde J, Verdijk J, Maier HB, Nordanskog P, van Wingen G, van Diermen L, Emsell L, Bouckaert F, Repple J, Camprodon JA, Wade BSC, Donaldson KT, Oltedal L, Kessler U, Hammar Å, Sienaert P, Hebbrecht K, Urretavizcaya M, Belge JB, Argyelan M, Baradits M, Obbels J, Draganski B, Philipsen A, Sartorius A, Rhebergen D, Ousdal OT, Hurlemann R, McClintock S, et al.
J Psychiatr Res. 2024;179:199-208.EEG measures of brain arousal in relation to symptom improvement in patients with major depressive disorder: Results from a randomized placebo-controlled clinical trial
Ulke C, Kayser J, Tenke CE, Mergl R, Sander C, Panier LY, Alvarenga JE, Fava M, McGrath PJ, Deldin PJ, McInnis MG, Trivedi MH, et al.
Psychiatry Res. 2024;342:116165.The gut-brain axis in depression: Are multi-omics showing the way?
Foster JA, Trivedi MH.
Cell Rep Med. 2024;5(9):101741.The physical activity in cancer survivors (PACES) trial: a factorial randomized trial to optimize intervention for breast cancer survivors.
Rethorst CD, Carmody TJ, Argenbright KE, Vazquez L, DeLuca T, Mayes TL, Hamann HA, Trivedi MH.
J Behav Med. 2024. doi: 10.1007/s10865-024-00518-x.Clinical and sociodemographic features of the Texas resilience against depression (T-RAD) study: Findings from the initial cohort.
Trivedi MH, Jha MK, Elmore JS, Carmody T, Chin Fatt C, Sethuram S, Wang T, Mayes TL, Foster JA, Minhajuddin A.
J Affect Disord. 2024;364:146-56.Longitudinal prediction of psychosocial functioning outcomes: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Section-II personality disorders versus alternative model personality dysfunction and traits
Clark LA, Ro E, Vittengl JR, Jarrett RB.
Personal Disord. 2024;15(5):341-51.Substance use patterns and mental health comorbidities in youth with a history of depression or suicidality: Findings from TX-YDSRN.
Clark SL, Dodd CG, Mitchell TB, Ingram SJ, Armstrong GM, Jha MK, Soares JC, Smith M, Minhajuddin A, Slater H, Wakefield SM, Trivedi MH.
J Affect Disord. 2024;366:210-6.Measurement invariance of the Screen for Child Anxiety Related Emotional Disorders (SCARED) across ethnicity, age, and sex among youth with depression.
Silva T, Spencer SD, Higham M, Castillo AA, Minhajuddin A, Gorman A, Goodman LC, Pinciotti CM, Hernandez S, Slater H, Soutullo CA, Hettema JM, Azhar NA, Goodman WK, Trivedi MH, et al.
Personalized Medicine in Psychiatry. 2024;47-8.