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These selected publications showcase research that spans fundamental T-cell biology, cancer immunology, and cellular therapy. Together, they highlight efforts to define the genetic and immune mechanisms underlying cancer and immune-mediated disease, identify novel therapeutic targets, and translate discoveries in human T-cell biology into next-generation immunotherapies and engineered cellular therapies.

2025

Journal of Clinical Investigation - April 15, 2025

Journal of Clinical Investigation - April 15

Addiction of primary cutaneous γδ T cell lymphomas to JAK/STAT signaling

Zhang, Y., Choi, J., et al. Journal of Clinical Investigation (2025). DOI: 10.1172/JCI180417

2024

Cancer Discovery - September 4, 2024

Cancer Discovery - September 4

Preexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy

Reinstein, Z.Z., Choi, J., et al. Cancer Discovery (2024). DOI: 10.1158/2159-8290.CD-23-0798

Nature - February 7, 2024

Nature - February

Naturally occurring T cell mutations enhance engineered T cell therapies

Garcia, J., Choi, J., et al. Nature (2024). DOI: 10.1038/s41586-024-07627-2

Nature - July 2024

Nature - July 10

Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus

Law, C., Choi, J., et al. Nature (2024). DOI: 10.1038/s41586-024-07845-8

2023

Nature Cancer - October 2023

Nature Immunology - October 16

PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma

Wartewig, T., Choi, J., et al. Nature Cancer (2023). DOI: 10.1038/s43018-023-00635-7

2021

Blood - October 7, 2021

Blood - October 7

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity

Park, J., Choi, J., et al. Blood (2021). DOI: 10.1182/blood.2020009655

2020

Nature Communications - April, 2020

Nature Communications - April 14

Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas

Daniels, J., Choi, J., et al. Nature Communications (2020). DOI: 10.1038/s41467-020-15572-7