Anas Khanshour, Ph.D.
Dr. Anas Khanshour is a Senior Data Scientist and Bioinformatics Lead for the NGS Clinical Laboratory in the Department of Pathology at UT Southwestern Medical Center (UTSW) in Dallas, Texas.
Originally from Douma, Syria, Dr. Khanshour earned his Ph.D. in Biomedical Sciences from Texas A&M University in 2013, where he also completed a teaching fellowship. He subsequently pursued postdoctoral training in human computational genomics at Scottish Rite Hospital for Children. From 2014 to 2022, he served as an Instructor of Biology and Adjunct Faculty at Texas A&M University.
Since joining the Pathology Department at UTSW in November 2023, Dr. Khanshour has led initiatives in clinical next-generation sequencing (NGS) data management, bioinformatics pipeline development, and the implementation of artificial intelligence (AI) technologies within molecular diagnostics. His work focuses on translating complex genomic data into clinically actionable insights that improve diagnostic accuracy, streamline laboratory workflows, and enhance patient care. By integrating large-scale genomic and clinical datasets, he helps advance precision medicine and supports the development of innovative diagnostic and therapeutic approaches for cancer and other complex diseases.
Dr. Khanshour's research spans cancer genomics, gene discovery, computational biology, and translational bioinformatics. He has authored more than 48 peer-reviewed publications, book chapters, and scientific abstracts, with a focus on applying advanced computational methods to address clinically relevant questions in Biology and human disease. He has served on the Board of Directors of the Texas Genetics Society and is the recipient of the Russell A. Hibbs Best Basic Research Award, Texas A&M Publication Excellence recognition, and multiple awards for scientific presentations.
Outside of his professional activities, Anas enjoys plant breeding, with a particular interest in rare and heirloom varieties, and has been an avid beekeeper for more than 25 years.
Key Publications
Khanshour A.M., et al. Exome sequencing reveals rare loss-of-function mutations in FLG and immune genes in patients with multiple food allergies. J Allergy Clin Immunol. 2026. Editor’s Choice.
Khanshour A.M., et al. Optimized Solid Tumor Next Generation Sequencing (NGS) Panel: Clinical Impact of Unique Informative Content Beyond Commercial Assays. The Journal of Molecular Diagnostics, 27, S1-S206(2025).
Khanshour, A.M., et al. Interval padding for the MSI calculation in targeted NGS solid cancer analysis. The Journal of Molecular Diagnostics, 26, S1-169(2024).
Cai, Q., Meng, X., Sun, J., Gagan, J., Aggarwal, A., Khanshour, A.M., Bhanvadia, R., Xu, J., Mohanty, S.K. & Shah, R.B. Prostate ductal adenocarcinoma revisited: clinicopathological and genomic characterization identifies heterogenous group of diseases with implications for patient management. Mod. Pathol. 38, 100743 (2025).
Yu, H.†, Khanshour, A.M.†, et al. Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis. eLife 12, RP89762 (2024). † Co-first authors.