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Javier Garcia Bermudez, Ph.D., an Assistant Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), is one of 67 scientists awarded a 2024 National Institutes of Health High-Risk, High-Reward Research grant.

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children’s Medical Center Research Institute at UT Southwestern published in Cell.

Children’s Health significantly expands access to pediatric behavioral health services

Scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a benefit of vitamin C deficiency: protection from a major parasitic disease.

Liver cells have a vital metabolic inflexibility during regeneration to starve dysfunctional cells and keep damage from spreading, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Science.

In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cancer Discovery, tumors with this metabolic activity result in early patient death.

Children’s HealthSM and UT Southwestern Medical Center unveiled plans for a new $5 billion pediatric health campus in Dallas’ Southwestern Medical District today. Spanning more than 33 acres, the new pediatric campus offers a patient-centric design that can meet the rapidly increasing need for more pediatric services ranging from the most common to the most complex.

Babies and toddlers who need a tracheostomy – a tube surgically inserted into their windpipe to help relieve breathing problems – are at a high risk of accumulating fluid behind their eardrum when on a ventilator.

Children's HealthSM, the leading pediatric health care provider in North Texas, and UT Southwestern Medical Center announce their first joint pediatric enterprise initiative at the Reimagine RedBird development to broaden access in southern Dallas to the region’s top pediatric care.

Contrary to how tumors operate while still in the kidney, metastatic kidney cancers rely heavily on mitochondrial metabolism, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.