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Meet the Sieber Lab team.

We are studying how these molecules work together to generate comets, and defining how actin contributes to vesicle traffic.

Meet the Michaely Lab team.

Michaely Lab teaching

Publications for Dr. Lindsay Cowell

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shunchun Yang1, Saleh Ramezani2, Zhiqiang Lin1, Yiguang Wang1, Xinpeng Ma1, Zhiqun Zeng1, Min Luo1, Esther de Boer3, Xian-Jin Xie4, Joel Thibodeaux5, Rolf A. Brekken6, Xiankai Sun2, Baran D. Sumer7

The McDermott Center Human Genetics Clinical Lab is dedicated to help accelerate the pace of human genetic research by providing skilled assistance with collecting and storing biologic specimens.

Articles https://doi.org/10.1038/s41551-019-0416-1 1Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. 3Children’s Research Institute, Departments of Pediatrics, Neuroscience, and Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. 4Department of Otolaryngology, University of Texas Southwestern

Structural Biology Lab researchers published these articles from 2010 through 2019

ARTICLE Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery F. J. Voskuil 1,13, P. J. Steinkamp 2,13, T. Zhao3, B. van der Vegt 4, M. Koller2, J. J. Doff4, Y. Jayalakshmi3, J. P. Hartung5, J. Gao 6,7, B. D. Sumer 6✉, M. J. H. Witjes1, G. M. van Dam 2,8✉ & the SHINE study group* Cancer cell metabolism leads to a uniquely acidic microenvironment in solid tumors, but exploiting the labile extracellular pH differences