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Instrumentation The core is equipped with seven mass-spectrometry platforms to provide a wide range of analyses to customers and collaborators. These instruments are housed in a purpose-built access-controlled facility with dedicated HVAC, and many power and network connections. This facility provides ample space and flexibility for future growth and instrument developments. Shotgun Proteomics Thermo Orbitrap Eclipse – This mass spectrometer was acquired by the core in 2022. The Eclipse is among

Glycosylation Introduction Glycosylation can be a very challenging PTM to analyze by mass spectrometry, in large part because of the multiple different sequences a glycan can have on a single site. Additionally, the glycan on a peptide can easily fall off in the mass spectrometer, making sequencing and localization challenging. However, with the Oribtrap Fusion Lumos and its capabilities to perform electron transfer dissociation (ETD) along with higher-energy collisional dissociation (HCD), we

UT Southwestern offers scholar funding programs that provide financial resources, career guidance, and protected research time to facilitate the early career development of physician-scientists who have high potential to conduct clinical research and advance research science.

The McDermott Center Human Genetics Clinical Lab is dedicated to help accelerate the pace of human genetic research by providing skilled assistance with collecting and storing biologic specimens.

library of past and current Clinical Research Update Newsletters

UT Southwestern fosters a rich collaboration among biostatisticians, epidemiologists, bioinformaticians, computer programmers, and database experts that supports clinical research projects.

UT Southwestern welcomes more than 10,000 patients and volunteers annually to participate in clinical research studies. To explore opportunities to participate in a study, please use StudyFinder online.

Protocol for immunohistochemistry and immunofluorescence frozen sections.

Protocol for immunofluorescence.

Review Study provides study submission protocols, coverage analysis documents, and industry agreement guidance.