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Access resourceful research-specific terms and definitions for research funding or conducting a research study.

Faculty Resources Employee Resources Human Research Protection Program Micro Navigation UTSW IRB sIRB Participants QA/Monitoring Regulatory Support Reportable Events News UTSW Serving as the sIRB Relying on External sIRB sIRB Definitions Relying on External sIRB UTSW Human Research Protection Program (HRPP) supports the requirement for single IRB review by collaborating with multiple External IRBs. Start-up Process to use External IRB An overview of the start-up process to use an External IRB is

SPA Negotiates Terms Once you establish a relationship with a sponsor for your clinical trial or patient treatment and have an agreement in place – you must submit the contract terms to Sponsored Programs Administration (SPA) for review and negotiations through eAgreements . View EPIC Care & MCSA View Master Agreements Please note: SPA manages the negotiation of clinical research industry and clinical and nonclinical non-industry research agreements. Department is not authorized to negotiate

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Faculty Resources Employee Resources Human Research Protection Program Micro Navigation UTSW IRB sIRB Participants QA/Monitoring Regulatory Support Reportable Events News UTSW Serving as the sIRB Relying on External sIRB sIRB Definitions UTSW Serving as the sIRB UTSW ca n serve as the si ngle IRB for multisite studies in most cases when required by the funding source or when single IRB will enhance efficiency and effectiveness of the review process. Decisions about whether to serve are made on a

Nikon Widefield Epi-scope (NL5.120R) Inverted Nikon EclipseTi with high-quality optics for widefield epifluorescence in fixed and live cells Motorized xy-stage for multi-point acquisition and tiling. Perfect Focus System to keep your sample in focus Excitation filters centered around 350, 405, 445, 488, 514, 555 and 645 nm 10x, 20x, 40x, 60x and 100x objectives with phase or DIC available Andor Zyla 5.5 sCMOS with large 2560x2160px field of view for fluorescence Teledyne Infinity3-6UR color

Dr. Daniela Nicastro has stepped down as Director of the Cryo-EM Facility at UT Southwestern.

Determination of Intracellular Compound Concentrations Occasionally large differences in compound potency in biochemical versus cell-based assays are noted. While protein binding may account for some of this discrepancy, we have on occasion noted differences in the extent to which different compounds accumulate inside of cells or the extent to which the same compound accumulates in different cells (1). We have developed an intracellular compound accumulation assay to measure the amount of

Profile on Keisha Hardeman, Ph.D., a postdoctoral scholar who researches Nonalcoholic Fatty Liver Disease in the PROVIDES program at UT Southwestern.