Fat cells genetically altered to overproduce a hormone called FGF21 resulted in improved metabolic health and an extended lifespan in mice that were fed a high-fat diet, UT Southwestern Medical Center researchers report. The findings, published in Cell Metabolism, could lead to new interventions

Adding targeted radiation to chemotherapy prior to surgery may offer better control of pancreatic tumors – potentially reducing the rate of recurrence after treatment, according to a new study from UT Southwestern Medical Center. Published in Clinical Cancer Research, the novel study offers evidence

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a

Artificial intelligence may soon play a critical role in choosing which depression therapy is best for patients.

Ravikanth Maddipati, M.D., Assistant Professor of Internal Medicine and in Children’s Medical Center Research Institute at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to support research investigating positional heterogeneity in cancer, or how tumors

Jinming Gao, Ph.D., Professor of Biomedical Engineering, Cell Biology, Otolaryngology – Head and Neck Surgery, and Pharmacology at UT Southwestern Medical Center, has been selected as a fellow of the National Academy of Inventors (NAI) in recognition of his efforts to develop innovative

Carlos L. Arteaga, M.D., Director of the Harold C. Simmons Comprehensive Cancer Center and Associate Dean of Oncology Programs at UT Southwestern Medical Center, and David Mangelsdorf, Ph.D., Chair and Professor of Pharmacology and Professor of Biochemistry, have been elected to the National Academy

James J. Collins III, Ph.D., Associate Professor of Pharmacology at UT Southwestern Medical Center who leads groundbreaking research into the parasitic disease schistosomiasis, has been named a Howard Hughes Medical Institute (HHMI) Investigator.

Gerta Hoxhaj, Ph.D., Assistant Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), is the recipient of the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) 2025 Mary Beth Maddox Award and Lectureship for her research in cancer metabolism.

David Mangelsdorf, Ph.D., Chair and Professor of Pharmacology and Professor of Biochemistry at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing