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A drug in clinical trials as a treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) works with a one-two punch that shuts down triglyceride production and fatty acid synthesis in liver cells, UT Southwestern Medical Center researchers show in a new study.

With knee replacement surgery becoming more common, Varatharaj Mounasamy, M.D., Professor of Orthopaedic Surgery at UT Southwestern Medical Center who specializes in hip and knee replacements, recommends taking off from work for a few weeks, joining a class to learn more about joint replacement, and

World health experts have long suspected that the incidence of COVID-19 has been higher than reported.

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced.

Pregnant women, who are at increased risk of preterm birth or pregnancy loss if they develop a severe case of COVID-19, need the best possible guidance on whether they should receive a COVID-19 vaccine.

A new drug combination discovered by the UT Southwestern Simmons Cancer Center may extend the effectiveness of a lung cancer treatment

Aggressive methods for reducing high blood sugar following a severe stroke are not more effective than standard, lower risk treatments, according to a new study that offers clarity to a long-debated issue in stroke care.

Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.

Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center