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A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

An experimental form of insulin administered just once a week was safe for patients with Type 2 diabetes and helped them maintain healthy blood sugar levels better than insulin injected daily, according to the results of a phase 3 clinical trial led by a UT Southwestern Medical Center researcher.

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests.

Liver cells have a vital metabolic inflexibility during regeneration to starve dysfunctional cells and keep damage from spreading, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Science.

UT Southwestern will lead a multisite initiative funded by the National Cancer Institute (NCI) to identify biomarkers to improve risk assessment and early detection of hepatocellular cancer (HCC), the most common form of liver cancer, among patients with cirrhosis.

Building upon previous work at UT Southwestern Medical Center, investigators report the results of a clinical trial exploring the role of stereotactic ablative radiation therapy (SAbR) for patients with a handful of metastases, or so-called oligometastatic disease.

UT Southwestern is ranked among the top 20 medical schools for primary care and the top 25 for research in the United States, according to U.S. News & World Report’s 2023 Best Graduate Schools rankings.

New findings by UT Southwestern researchers help better understand the how one of the most commonly mutated genetic drivers of cancer passes signals that cause the disease.

A relative decline in wealth during midlife increases the likelihood of a cardiac event or heart disease after age 65 while an increase in wealth between ages 50 and 64 is associated with lower cardiovascular risk, according to a new study in JAMA Cardiology.