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Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows.

As a young man in his mid-20s, Jorge Gómez was one of thousands of Cuban citizens who fled communism and the island country on a raft in 1994. He would spend 11 months living in a tent city at Guantanamo Bay before being granted asylum in the U.S., where he overcame numerous obstacles to build a

The CLOCK gene, which serves as a master controller of circadian rhythms, may play a key role in the extraordinary cognitive abilities of humans as well as neuropsychiatric disorders that afflict them, UT Southwestern Medical Center researchers report.

Inactivating a gene in young songbirds that’s closely linked with autism spectrum disorder (ASD) prevents the birds from forming memories necessary to accurately reproduce their fathers’ songs, a new study led by UT Southwestern shows.

Using a tool called Automated Meiotic Mapping (AMM) that was developed at UT Southwestern Medical Center, a team of researchers has identified a gene that appears to be key for regulating food intake.

Using a cutting-edge imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that’s crucial to the survival of malignant cells in some leukemias, lymphomas, and multiple myelomas.

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

A grid of electrodes placed on the backs of study participants delivered enough low-voltage electrical stimulation through the skin to change the short-term function of spinal cord neurons, a study led by UT Southwestern Medical Center researchers showed.

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere

– A “clot-busting” drug recently approved to treat acute ischemic strokes (AIS) that can be delivered quickly works as well as a decades-old medication used by most hospitals in the U.S. and could hold significant advantages for some patients, a study led by a UT Southwestern Medical Center