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Protein plays dual role in causing, preventing sepsis: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-protein-preventing-sepsis.html

A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.

Samuel Achilefu, Ph.D., elected to National Academy of Engineering: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-achilefu-elected-nae.html

Samuel Achilefu, Ph.D., inaugural Chair of Biomedical Engineering at UT Southwestern Medical Center and an internationally recognized leader in the fields of molecular imaging of cancer and nanotherapeutics, has been elected to the National Academy of Engineering (NAE).

Neurostimulation shows promise as potential Alzheimer’s treatment : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-neurostimulation-alzheimers-treatment.html

Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of

UTSW scientists identify cancer-suppressing genetic mutation: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-cancer-suppressing-gene.html

UT Southwestern Medical Center researchers identified a genetic mutation that slows the growth of melanoma and potentially other cancers by harnessing the power of the immune system. Their findings, published in the Journal of Experimental Medicine, could lead to new treatments that improve outcomes

Stimulating fat cells with GIP receptor has potential to treat obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-fat-cells-with-incretin.html

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

Why do women have more trouble after knee injuries? UTSW model explains: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-women-knee-injuries.html

A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds light on why women tend to have worse outcomes after knee injuries than men. Their findings, published in Scientific Reports, could facilitate research into new therapies for

Autoimmune skin condition linked to higher risk of heart disease: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-autoimmune-skin-condition.html

Patients with cutaneous lupus erythematosus (CLE), an autoimmune disease that causes skin inflammation, have a higher risk for atherosclerotic cardiovascular disease (ASCVD), or hardening of the arteries, UT Southwestern Medical Center researchers found.

Experimental depression treatment preserves cognitive function: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-experimental-depression-treatment.html

An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), a clinical trial led by UT Southwestern Medical Center researchers showed.

Active phase calorie restriction enhances longevity, UT Southwestern neuroscience study reveals : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/active-phase-calorie-restriction.html

A new study in mice led by neuroscientists at UT Southwestern’s Peter O’Donnell Jr. Brain Institute shows that it’s not just calories that count, but also when they’re consumed.

UTSW researchers use DNA analysis to diagnose subtypes of heart disease – UT Southwestern Medical Center psychiatric hospital: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-subtypes-of-heart-disease.html

The human heart is an intricate, complex organ and, like a car that starts sputtering, its function deteriorates for all sorts of reasons.