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Researchers led by a team at UT Southwestern Medical Center have identified cellular and molecular features of the brain that set modern humans apart from their closest primate relatives and ancient human ancestors. The findings, published in Nature, offer new insights into human brain evolution.

Mitochondria that power cellular activity fragment and change shape in breast cancer cells that migrate to the brain, an adaptation that appears necessary for the cells to survive, UT Southwestern Medical Center researchers report in a new study. The findings, published in Nature Cancer, could lead to new ways to prevent brain metastases, or the spread of cells from primary tumors to the brain.

Whether it’s after a natural disaster, a fatal shooting, or a tragedy closer to home, parents may find themselves trying to navigate difficult conversations with their children. What to say is just as important as what not to say, according to experts at UT Southwestern Medical Center. Children are naturally curious and may have questions, or they may be worried about their own safety.

UT Southwestern Medical Center researchers have identified hundreds of genomic variants associated with autism spectrum disorder (ASD) in East African families who have a markedly higher prevalence of the neurodevelopmental condition than other areas worldwide.

It’s almost that dreaded time of year, when spring and summer allergies can make life miserable for many.

The resilience and coping abilities of post-liver transplantation patients vary and change over time and are often linked to sociodemographic factors including income, race, and education, a study led by UT Southwestern Medical Center researchers shows.

Patients with sickle cell disease (SCD) who undergo total knee replacement are at higher risk for complications than non-SCD patients, according to a large-scale, retrospective study by researchers from UT Southwestern Medical Center and the University of Calgary.

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

UT Southwestern Medical Center will lead a national multicenter clinical trial to test a treatment strategy for pediatric cancer patients that has shown promising results in adults.

– The brain circuitry that is disrupted in Alzheimer’s disease appears to influence memory through a type of brain wave known as theta oscillation, a team led by UT Southwestern Medical Center researchers report.