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In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology

– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

Surgical nerve decompression, used to treat conditions such as carpal tunnel syndrome and sciatica, could play a role in relieving the pain of diabetic neuropathy patients, researchers at UT Southwestern Medical Center found.

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues.

– AccessHope, LLC, a company changing the way leading-edge cancer expertise is delivered, announced that UT Southwestern Harold C. Simmons Comprehensive Cancer Center will become the seventh National Cancer Institute (NCI)-designated center in the AccessHope network.

UT Southwestern Medical Center has joined more than a dozen leading medical centers and Microsoft to form the Trustworthy & Responsible AI Network (TRAIN), a national group designed to set standards and safely explore applications of artificial intelligence (AI) in health care.

Millions of children have food allergies, many of which can cause severe illness or death. In a study published in the New England Journal of Medicine, a team of researchers, including those from UT Southwestern, shows in a phase three clinical trial that an antibody-based therapy called omalizumab may inhibit food allergy reactions when delivered repeatedly over time.

The composition of the gut microbiomes in a group of rectal cancer patients reveals distinct signatures by race, ethnicity, and age of onset, with white Hispanics showing significant presence of one specific bacteria, UT Southwestern Medical Center researchers report.

At exactly 11 a.m. Friday, surrounded by family, friends, and mentors, 224 members of UT Southwestern Medical School’s Class of 2024 – who all embarked on their medical education during the height of the COVID-19 pandemic – learned where they will continue their medical training.

For decades, researchers have assumed that women taking oral contraceptives have stable levels of sex hormones over each monthly cycle. However, a new study in the American Journal of Physiology-Endocrinology and Metabolism led by Yasin Dhaher, Ph.D., Professor of Physical Medicine & Rehabilitation and Orthopaedic Surgery at UT Southwestern Medical Center, shows that the opposite is true.