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The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical Center reported in a retrospective study.

A novel speech analysis tool that uses artificial intelligence was highly accurate in detecting mild cognitive impairment and dementia in a Spanish-speaking population, according to research led by UT Southwestern Medical Center.

UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren’t equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

For decades, researchers have assumed that women taking oral contraceptives have stable levels of sex hormones over each monthly cycle. However, a new study in the American Journal of Physiology-Endocrinology and Metabolism led by Yasin Dhaher, Ph.D., Professor of Physical Medicine & Rehabilitation and Orthopaedic Surgery at UT Southwestern Medical Center, shows that the opposite is true.

A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.

– Strong family relationships have long been associated with a better sense of well-being and connection. Now a research team led by UT Southwestern Medical Center has linked the quality of those relationships with how successfully people – particularly aging African Americans – manage pain.

A unique collaboration between two UT Southwestern Medical Center labs – one that studies bacteria and another that studies viruses – has identified two immune proteins that appear key to fighting infections.

Stem cell biologist Sean J. Morrison, Ph.D., has been elected by his peers as an associate member of the European Molecular Biology Organization (EMBO).

Researchers at UT Southwestern Medical Center have developed a machine learning model that can identify patients with diabetic cardiomyopathy, a heart condition characterized by abnormal changes in the heart’s structure and function that predisposes them to increased risk of heart failure.