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– A widely used fracture risk calculator may help guide surgical decisions to treat patients with an endocrine disorder called primary hyperparathyroidism (PHPT) that causes progressive bone loss, according to a study led by UT Southwestern Medical Center researchers.

Complications after an amputation left Scott Bryson, a 50-year-old father of three, unable to walk. But in June 2023, he took his first steps in nearly a decade after receiving a revolutionary surgical procedure at UT Southwestern Medical Center.

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

A UT Southwestern Medical Center quality improvement team led a large-scale, multispecialty project in partnership with the Parkland Center of Innovation and Value to help patients with implantable cardioverter defibrillators (ICDs) better understand their devices and make choices about their care.

While randomized comparative trials are needed, a relatively new treatment option for upper urinary tract cancers shows promise for lowering long-term recurrence in many patients with low-grade disease, according to a multicenter study led by researchers at UT Southwestern Medical Center.

Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of Alzheimer’s Disease, indicate that while future trials are needed, neurostimulation shows early promise as a treatment for Alzheimer’s and other neurodegenerative disorders, such as Lewy body dementia.

A novel combination of drugs successfully killed breast cells carrying double mutations in the HER2 gene that had rendered them resistant to a commonly used cancer therapy, a study led by UT Southwestern Medical Center researchers showed.

Todd Aguilera, M.D., Ph.D., Assistant Professor of Radiation Oncology and member of the Experimental Therapeutics Program in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center, has been named one of 11 inaugural Cancer Moonshot Scholars. The national program recognizes a cohort of early-career investigators from underrepresented groups who have been identified as emerging leaders in cancer research and innovation.

Only 22% of Texas patients with early-stage pancreatic cancer received standard-of-care surgery to remove their tumors, researchers at UT Southwestern Medical Center report in a new study.

Zhijian “James” Chen, Ph.D., Professor of Molecular Biology at UT Southwestern Medical Center, has been awarded the 2023 Louisa Gross Horwitz Prize in recognition of his groundbreaking work on innate immunity.