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The Laboratory for Molecular Diagnostics uses cutting-edge molecular techniques to help answer difficult diagnostic problems.

Find out how to contact the Division of Surgical Oncology in the Department of Surgery at UT Southwestern.

Establish a Relationship details how to identify a sponsored program that might be a good fit and cultivate a sponsor relationship.

UT Southwestern Medical Center offers Cytogenomic Microarray Analysis (CMA) Laboratory services to pathologists.

Immigration update on student status terminations.

Donors may contribute to an endowment fund to help establish the Dr. Douglas and Diane Sinn Chair in Oral and Maxillofacial Surgery at UT Southwestern.

Computing and Data Analysis Continuous improvement in mass-spectrometry instrumentation means that proteomics facilities are generating a growing amount of data, and tackling increasingly complex datasets. The rise of quantitative proteomics in particular demands robust data analysis techniques to en…

General Limitations MS proteomics is a powerful tool for the analysis of protein samples, but there are some limits to the techniques we employ in the Proteomics Core. Knowing the limitations of the services we provide can help to ensure your experiment is a success, and you do not incur costs for un…

Intact Mass What do we use to measure the mass of intact proteins? We do LC/MS analysis of intact proteins using a Q-TOF mass spectrometer with electrospray ionization. This means that samples must be free of detergents. An ideal solvent is 5% acetonitrile in water containing 1-5% formic acid or acet…

PTM Identification Introduction The presence or absence of post-translational modifications (PTMs), such as phosphorylation, on a protein are often as interesting as the presence of absence of the protein itself. The PTM ID service offers identification of PTMs on a protein from a purified protein or…