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Cardio health decline tied to midlife wealth: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/cardio-health-decline-tied-to-midlife-wealth.html

A relative decline in wealth during midlife increases the likelihood of a cardiac event or heart disease after age 65 while an increase in wealth between ages 50 and 64 is associated with lower cardiovascular risk, according to a new study in JAMA Cardiology.

How cancer cells don their invisibility cloaks - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/how-cancer-cells-don-their-invisibility-cloaks.html

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results.

Understanding the circadian clocks of individual cells: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/understanding-the-circadian-clocks-of-individual-cells.html

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means.

The secret of lymph: How lymph nodes help cancer cells spread : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/lymph-nodes-help-cancer-cells-spread.html

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream.

Tumors hijack the cell death pathway to live: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/tumors-hijack-the-cell-death-pathway-to-live.html

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response

UT Southwestern cancer researchers uncover antitumor mechanisms to help improve radiation therapy: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/antitumor-mechanisms-to-help-improve-radiation-therapy.html

An international team of cancer researchers has identified important mechanisms that activate antitumor immune response during radiation therapy

Scientists identify cells responsible for liver tissue maintenance and regeneration: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/scientists-identify-cells-responsible-for-liver-tissue.html

While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery.

Giving brown fat a boost to fight Type 2 diabetes: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/brown-fat-a-boost-to-fight-type-2-diabetes.html

Increasing a protein concentrated in brown fat appears to lower blood sugar, promote insulin sensitivity, and protect against fatty liver disease by remodeling white fat to a healthier state.

Cryo-EM imaging of STING protein reveals new binding pocket: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/cryo-em-imaging-of-sting-protein.html

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

Breaking it down: How cells degrade unwanted microRNAs : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/how-cells-degrade-unwanted-micrornas.html

UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.