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Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

DNA that ends up where it doesn’t belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes.

A new nanoparticle-based drug can boost the body’s innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

Fusing the neck’s top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study.

UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories.

Inactivating a gene in young songbirds that’s closely linked with autism spectrum disorder (ASD) prevents the birds from forming memories necessary to accurately reproduce their fathers’ songs, a new study led by UT Southwestern shows.

Early in his career, Ralf Kittler, Ph.D., attracted the attention of academic leaders at UT Southwestern Medical Center with his studies of DNA transcription factors and their role in tumor growth and suppression.

Jean-Laurent Casanova, M.D., Ph.D., an internationally recognized expert in the fields of genetics, immunology, and infectious diseases who will be joining UT Southwestern Medical Center on July 1, has been selected along with a global team of researchers to receive a Cancer Grand Challenges award of up to $25 million.

The Centers for Medicare & Medicaid Services (CMS) announced that the Southwestern Health Resources Accountable Care Network (SWHR) saved more than $52 million in 2019.