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A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases. The study, published in Nature Communications, offers key insights that could help identify new treatments for patients.

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

Patients overwhelmingly prefer to receive test results as soon as they are available on online medical portals, even if it means viewing the results prior to discussing them with their doctor, a new study co-led by UT Southwestern and Vanderbilt University researchers reports.

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

About 1 million people in the United States have Parkinson’s disease, a progressive neurological disorder that ranks second to Alzheimer’s among the most common neurodegenerative diseases.

With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.

Combat wounds to a soldier’s genital area are not as well understood as those to other parts of the body because of the intimate nature of the injuries.

UT Southwestern Medical Center is one of seven health systems in the nation being recognized for its leadership development initiatives, the latest in a series of national and regional employer honors.

UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.

Magnetic resonance imaging (MRI) can reliably establish measurements for anterior cruciate ligament (ACL) “footprints” that are critical to the placement of grafts for reconstruction surgery, UT Southwestern researchers report.