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In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cancer Discovery, tumors with this metabolic activity result in early patient death.

Two new studies suggest Medicare’s system of penalizing hospitals if too many patients are readmitted within 30 days should also look at whether the patients were well enough to remain in their home during that time.

Two studies led by UT Southwestern researchers shed new light on how the brain encodes time and place into memories.

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity.

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced.

Scientists with UT Southwestern’s Peter O’Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication.

Ravikanth Maddipati, M.D., Assistant Professor of Internal Medicine and in Children’s Medical Center Research Institute at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to support research investigating positional heterogeneity in cancer, or how tumors in the same organ can behave differently based on where they form.

Reducing the level of body fat and waist size are linked to a lower risk of heart failure in patients with type 2 diabetes, a study led by UT Southwestern researchers indicates.

Blood pressure readings taken from neuroscience intensive care unit (NSICU) patients had marked differences between opposite sides of the body and different anatomical sites in each individual