Publications
Recent Publication Highlights
- 2026 Articles
Isotype-specific optimization of antigen-specific ELISA reveals differential effects of blocking reagents.
Juan Shugert, Drashya Sharma, Anne B Satterthwaite, J David Farrar. Journal of Immunological Methods.An Fc receptor and IgA functional signature identifies TB disease in children living with HIV.
Ye Jin Kang, Nannan Wang, Amyn Malik, Pei Lu, Alison Grossman, Irene Njuguna, Elizabeth Maleche-Obimbo, Sylvia M LaCourse, Jennifer Slyker, Dalton Wamalwa, Grace C John-Stewart, Chuangqi Wang, Lisa Marie Cranmer, Lenette L Lu. Journal of the Pediatric Infectious Diseases Society.ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways.
James S Ye, Elena Purlyte, Victor A Lopez, Jericha Mill, Lexus Tatge, Thomas Kizzar, Dominique Baldwin, Edrees Rashan, Juhee Kim, David J Pagliarini, Diana R Tomchick, Krzysztof Pawłowski, Peter M Douglas, Judith Simcox, Vincent S Tagliabracci. bioRxiv.The factory enters the fray: how mitochondrial protein trafficking shapes the host response to infection.
Dustin C Hancks, Steven F Baker. Journal of Virology.Digital PCR quantification of Treponema pallidum burden in primary syphilis lesion swabs reveals variable performance across direct detection methods.
Hayden Z Smith, Manoj K Sah, Joey Stringer, Danilo DaSilva, Suzanne Wada, Amanda Evans, Emily H Adhikari, Jeffrey A SoRelle. Diagnostic Microbiology and Infectious Disease.SMURF2 inhibits autophagic control of Mycobacterium tuberculosis in macrophages.
Priscila C Campos, Kathryn C Rahlwes, Victoria A Ektnitphong, Beatriz Rs Dias, Kubra F Naqvi, Samuel Alvarez-Arguedas, Michael U Shiloh. JCI Insight.Salmonella lipopolysaccharide stimulates uptake of long-chain fatty acids in the small intestine.
Eugene Koo, Gabriella Quinn, Cassie L Behrendt, Brian Hassell, Katie N Kang, Kelly A Ruhn, Gonçalo Vale, Jeffrey G McDonald, Wenhan Zhu, Sebastian E Winter, Lora V Hooper. Proceedings of the National Academy of Sciences of the United States of America.Pseudomonas aeruginosa Impairs Mitochondrial Function During Infection of Corneal Epithelial Cells.
Rajalakshmy Ayilam Ramachandran, Joelle T Abdallah, Abigail M Blanton, Mahad Rehman, Hamid Baniasadi, Danielle M Robertson. Investigative Ophthalmology & Visual Science.Desynchronization of intestinal circadian clocks and gastrointestinal dysfunction.
Yuuki Obata, Shin Yamazaki. Nature Reviews Gastroenterology & Hepatology.Antibiotic-Releasing Porous Shell Cements.
Trang N Hau, Celine J Agnes, Lauren E Kemp, Walid K Bibi, Cole C Moore, Benjamin Levi, Antonia F Chen, Alexander M Tatara. Antibiotics (Basel, Switzerland).Sorting nexin 5 deficiency impairs MHC class II antigen presentation and inflammatory responses during tuberculosis.
Beatriz R S Dias, Kubra F Naqvi, Victoria A Ektnitphong, Samuel Alvarez-Arguedas, Kathryn C Rahlwes, Priscila C Campos, Michael U Shiloh. The Journal of Immunology.An injury-responsive bHLH is required for regenerative responses following mechanical injury in adult Schistosoma mansoni.
Lu Zhao, James J Collins. bioRxiv.Targeting of ELMO2 by the Shigella E3 Ligase IpaH4.5 Reveals Key Differences Between ELMO Paralogs.
David F Schad, Maarten F de Jong, Dahee Seo, Benjamin L Kocsis, Neal M Alto. bioRxiv.The vesicular stomatitis virus matrix protein promotes FACT subunit depletion to suppress the FEAR pathway.
Emily A Rex, Dahee Seo, Aaron Embry, Neal M Alto, Don B Gammon. PLOS Pathogens.Reproductive health guidance for the cystic fibrosis community: a Cystic Fibrosis Foundation Position Paper.
Raksha Jain, Jennifer L Taylor, Traci M Kazmerski, Kevin Lonabaugh, Aaron Trimble, Danielle Velez Leitner, Kimberly Foil, Gina Hong, William B Johns, Teodora Kolarova, Ellen Meier, Annette Perry, Kathryn E Singh, Chelsea Stahl, Sylvia Szentpetery, Marissa S Weiss, Natalie E West, Alexandra Wilson, Brittany Wright, A Whitney Brown, Sarah E Hempstead, Paula Lomas, Peter G Middleton, Michal Shteinberg, Imogen Felton, Andrea H Roe. The Lancet Respiratory Medicine.Cannabis Is Associated With Potentially Proatherogenic Inflammation in Youth.
Theodoros Kelesidis, Leila Fotooh Abadi, Pratik Lama Tamang, Katherine Hampilos, Reece Fong, Joshua Sanchez, Isabelle Ruedisueli, Jeffrey Gornbein, Ziva D Cooper, Holly R Middlekauff. Circulation Research.Bacterial and human exonucleases mediate interkingdom antiviral immunity.
Courtney R Santos, Alyaa El-Guindy, Aaron Embry, Arabella E Martin, Neal M Alto, Don B Gammon, Kevin J Forsberg. bioRxiv.Pglyrp1-Cre marks distinct epithelial and immune lineages across mucosal sites.
Samuel Alvarez-Arguedas, Michael U Shiloh. ImmunoHorizons.The Campylobacter jejuni flagellar V-ring discerns viscosity levels to alter swimming velocity, metabolic gene expression, and fitness.
Deborah A Ribardo, Nanki K Singh, Morgan Beeby, David R Hendrixson. Proceedings of the National Academy of Sciences of the United States of America.Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance.
Animesh A Mishra, Suzette N Palmer, Christina M Zarek, Laura A Coughlin, Nicole Poulides, Jana Dakour, Rebecca S Chiu, Parastoo Sabaeifard, Wenling Li, Aidan C Morrill, Jiwoong Kim, Shuheng Gan, Cassie L Behrendt, Monika I Antczak, Xiaowei Zhan, Sebastian E Winter, Joseph M Ready, Lora V Hooper, Andrew Y Koh. Cell Host & Microbe.Ex vivo modeling of nasal epithelial airway inflammation in respiratory viral infections.
Leila Fotoohabadi, Arnaud John Kombe Kombe, Pratik Lama Tamang, Steven Klawinsky, Matthew Mitakidis, Kamilla Ablyazova, Richard Pyles, Theodoros Kelesidis. Frontiers in Microbiology.Not all gut cellular circadian oscillators are food entrainable.
Isabel Magaña, S K Tahajjul Taufique, Yongli Shan, Melody Shen, David E Ehichioya, Joseph S Takahashi, Shin Yamazaki, Yuuki Obata. Proceedings of the National Academy of Sciences of the United States of America.CMPK2 restricts Mycobacterium tuberculosis replication and regulates macrophage gene expression.
John Neff, Victoria A Ektnitphong, Priscila C Campos, Kubra F Naqvi, Beatriz R S Dias, Kathryn C Rahlwes, Zhenyu Zhong, Michael U Shiloh. bioRxiv.Oligonucleotide genetics for Pseudomonas aeruginosa enables high throughput hypomorph screening.
Sundar Pandey, Ayesha M Ahmed, Kanna Nagamatsu, Melissa Reyes, Jiwoong Kim, Xiaowei Zhan, David E Greenberg, Scott H Saunders. bioRxiv.B3GNT7 regulates mucin glycosylation and protects against colitis and infection.
Mary W N Burns, Joann Chongsaritsinsuk, Daniel C Propheter, Jianyi Yin, Vivian Zuo, Chin Huang, Lan Peng, Kelly A Ruhn, Kelley W Moremen, Ezra Burstein, Lora V Hooper, Stacy A Malaker, Jennifer J Kohler. bioRxiv.Mpi-driven N-glycosylation orchestrates mucin O-glycosylation and intestinal homeostasis.
Avishek Roy, Steve Meregini, Hye-Jeong Cho, Zhenglan Chen, Aariz Zaki, Tandav Argula, Bruce Beutler, Jeffrey A SoRelle. Nature Communications.Circadian Clock Programming of Anticipatory Antiviral Immunity Gates Enteric Virus Infection Susceptibility.
Temitope O Oshinowo, Robert W Maples, Mikal A Woods Acevedo, Broc T McCune, Hunter Dalton, Ishea Johnson, Devin A Simpkins, Urbashi Basu, Chaitanya Dende, Vera L Tarakanova, Julie K Pfeiffer, John F Brooks. bioRxiv.Myeloid cell IL-15 production in the brain supports bystander CD8+ T cell neuropathic immune responses following virus infection.
Jennifer N Berger, Alayna Rosales, Dustin Heiden, Camille Merrick, Brendan Monogue, J David Beckham, Leslie Berg. The Journal of Immunology.RNAP-seq: in vitro genome-scale transcription reveals preferential RNA polymerase pausing on Clostridioides difficile antisense DNA.
Ping Shen, Michael B Wolfe, Jason Saba, Rachel Mooney, Yu Bao, Ezaz Ahmad, Robert Landick, Xinyun Cao. bioRxiv.TIR-like NADases act in bacterial immunity and the RNA vault.
Adam Osinski, Benjamin Mayro, Victor A Lopez, Jason Schrad, Hannah Choi, Diana R Tomchick, Krzysztof Pawłowski, Kevin Forsberg, Sarah H Shahmoradian, Vincent S Tagliabracci. bioRxiv.MycoPLEX: Multiplexed fragment analysis for mycobacterial species and subspecies identification.
Ray Zhang, Manoj K Sah, Andrew E Clark, Jeffrey A SoRelle. Diagnostic Microbiology and Infectious Disease.Linkage between HLA-B8 and HLA-DQ2.5 Contributes to Ancestry-Dependent Genetic Risk for Celiac Disease.
Xin Long, Hemanth Karnati, Wenjing Ying, Mary-Joe Touma, Ioana Smith, Suzanne Lewis, Chao Xing, Ezra Burstein, Peter Hr Green, Michele J Alkalay, Alexandre Bolze, Xiao-Fei Kong. medRxiv.CORR Insights®: S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.
Alexander M Tatara. Clinical Orthopaedics and Related Research.Endometrioid Versus Seromucinous Borderline Ovarian Tumors: Divergent Molecular Signatures and a Shared Role as Precursors to Endometrioid Carcinoma.
Shuang Niu, Kyle Molberg, Kelley Carrick, Glorimar Rivera Colon, Katja Gwin, Wenxin Zheng, Jeffrey A SoRelle, Diego H Castrillon, Elena Lucas, Hao Chen. International Journal of Gynecological Pathology: Official Journal of the International Society of Gynecological Pathologists.Liver cirrhosis among females with cystic fibrosis using hormonal contraception.
Jennifer Chin, Monika Sarkar, Amalia S Magaret, Chialing Hsu, Natalie West, Patricia Walker, Elinor Langfelder-Schwind, Jennifer L Taylor-Cousar, Sigrid Ladores-Barrett, Denis Hadijiliadis, Andrea H Roe, Ahmet Uluer, Sheila Mody, Raksha Jain, Leigh Ann Bray Dayton, Emily M Godfrey. Contraception.STING signaling modulation by COPII cargo recognition.
Heng Lyu, Cong Xing, Wanwan Huai, Kun Song, Devon Jeltema, Hui Zhang, Xuewu Zhang, Nan Yan. Cell.NLRP1B is an integrated decoy that subverts Shigella flexneri E3 ligase activity to promote effector-triggered immunity.
Siwon Chung, Hannah Hudson, Kaitlin A Stromberg, Andrew Sandstrom. Proceedings of the National Academy of Sciences of the United States of America.Epithelial sensing of vitamin A shapes intestinal antimicrobial defense.
Gabriella Quinn, Daniel C Propheter, Kartik Kulkarni, Matthew Johnson, Gonçalo Vale, Jeffrey G McDonald, Ann Johnson, Brian Hassell, Cassie L Behrendt, Nikhil V Munshi, Lora V Hooper. bioRxiv.Type I interferon signaling promotes mucosal inflammation in murine models of colitis.
Jianyi Yin, Rodrigo Galicia Pereyra, Luis Sifuentes-Dominguez, Emre E Turer, Ezra Burstein. bioRxiv.Inhibition of FicD-mediated AMPylation and deAMPylation by isoprenoid diphosphates.
Aubrie M Blevins, Wei Peng, Lisa N Kinch, Zihan Monshad, Andrea G Paredes, Christina Volz, Jared Rutter, Amanda K Casey, Kevin G Hicks, Kim Orth. Proceedings of the National Academy of Sciences of the United States of America.PARP7 protects the lung epithelial barrier from diverse environmental threats.
Devon Jeltema, Kun Yang, Joshua J Baty, Antonina Araszkiewicz, Cong Xing, Kennady Knox, Zhen Tang, Nicole Dobbs, Nan Yan. Proceedings of the National Academy of Sciences of the United States of America.Hypofucosylation promotes pertussis toxin binding to cell surface glycococonjugates and pertussis toxin-induced intracellular ERK signaling.
Rohit Sai Reddy Konada, Nicole Nischan, Aurora Silva, Jennifer J Kohler. Glycobiology.Publisher Correction: PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling.
Jay Xiaojun Tan, Bo Lv, Jie Li, Tuo Li, Fenghe Du, Xiang Chen, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature.Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing.
Maria Sindhura John, Mahendran Chinnappan, Camille I Sturges, Methinee Artami, Mohini Bhattacharya, Rebecca A Keogh, Jeffrey S Kavanaugh, Shivani Jain, Hanna Gedamu, Jessica Komarovsky, Mauricio Velasquez, Tripti Sharma, Jeffrey G McDonald, Alexander R Horswill, Tamia A Harris-Tryon. Nature Microbiology.STING takes on RNA viruses.
Nan Yan. Science.Antiviral innate immunity induces alpha synuclein phosphorylation at serine129 in neurons independent of aggregation.
Dustin L Heiden, Camille Merrick, Robert C Evans, Alexander J Rajic, Madeline Slater, Ravi Mahalingam, Vicki Traina-Dorge, Jennifer N Berger, Leslie J Berg, J David Beckham. npj Parkinson's Disease.PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling.
Jay Xiaojun Tan, Bo Lv, Jie Li, Tuo Li, Fenghe Du, Xiang Chen, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature.Sorting nexin 5 mediates antigen presentation and immunity against Mycobacterium tuberculosis.
Beatriz R S Dias, Kubra F Naqvi, Victoria A Ektnitphong, Samuel Alvarez-Arguedas, Kathryn C Rahlwes, Priscila C Campos, Michael U Shiloh. bioRxiv.Deubiquitinase USP15 restricts LC3-dependent targeting of Mycobacterium tuberculosis.
Kathryn C Rahlwes, Priscila C Campos, Beatriz R S Dias, Paola K Párraga Solórzano, Michael U Shiloh. Autophagy.Cysteine Reactivity Profiling Identifies Host Regulators of Mycobacterium tuberculosis Replication in Human Macrophages.
John K Neff, Kristen E DeMeester, Paola K Párraga Solórzano, Radu M Suciu, Melissa M Dix, Gabriel Simon, Max A Gianakopoulos, Bruno Melillo, Benjamin F Cravatt, Michael U Shiloh. ACS Infectious Diseases.A single-cell atlas of intestinal immune cells across the day-night cycle reveals dynamic populations.
Robert W Maples, Gabriella Quinn, Tarun Srinivasan, Chaitanya Dende, Lora V Hooper, Julie K Pfeiffer. bioRxiv.Disability and Health Care Interactions in Patients with Celiac Disease in the United States: An Analysis of All of Us Cohort.
Bettina Anil, Jonathan Govrin, Duojian Kongcao, Hemanth Karnati, Peter H R Green, Xiao-Fei Kong, Benjamin Lebwohl. Journal of Clinical Gastroenterology.Exome sequencing reveals rare loss-of-function mutations in FLG and immune genes in patients with multiple food allergies.
Anas M Khanshour, Cynthia Haddad, Steve Meregini, Mellisa Zamudio, Amy Arneson, Christopher Parrish, J Andrew Bird, Jeffrey A SoRelle. The Journal of Allergy and Clinical Immunology.BACH2 dosage establishes the hierarchy of stemness and fine-tunes antitumor immunity in CAR T cells.
Taidou Hu, Ziang Zhu, Ying Luo, Safuwra Wizzard, Jonathan Hoar, Sejal S Shinde, Kiddist Yihunie, Chen Yao, Tuoqi Wu. Nature Immunology.Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity.
Danhui Liu, Chuanli Zhou, Xiaochen Wang, Zhou Luo, Ruiyao Xu, Shanshan Huo, Lina Guo, Xuemei Luo, Shuhan Yang, Arielle Click, Janiece Vancil, Paola Barajas, Victor Mijares, Hamid Baniasadi, Nan Yan, Jan Rehwinkel, Dustin C Hancks, Elizabeth H Chen, Shuang Liang, Zhenyu Zhong. Science.Single-Cell Clonal Lineage Tracing Identifies the Transcriptional Program Controlling the Cell-Fate Decisions by Neoantigen-Specific CD8+ T Cells.
Ying Luo, Taidou Hu, Chen Yao, Tuoqi Wu. Cancer Immunology Research.Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
James S Ye, Abir Majumdar, Brenden C Park, Miles H Black, Ting-Sung Hsieh, Adam Osinski, Kelly A Servage, Kartik Kulkarni, Jacinth Naidoo, Neal M Alto, Margaret M Stratton, Dominique Alfandari, Joseph M Ready, Krzysztof Pawłowski, Diana R Tomchick, Vincent S Tagliabracci. The EMBO Journal.Developing antisense oligomer biotics "asobiotics" as precision antibacterials: designs, strategies, and considerations for future success.
Dina A Moustafa, Chandradhish Ghosh, Jakob Jung, Amila Nanayakkara, Madhab Sapkota, Kanna Nagamatsu, Bruce Geller, Jörg Vogel, Joanna B Goldberg, David E Greenberg. FEMS Microbiology Reviews.Innate immune sensing via the cGAS-STING pathway restricts extrachromosomal DNA-driven tumorigenesis.
Tuo Li, Qing-Lin Yang, Kailiang Qiao, Anli Zhang, Chenglong Sun, Huocong Huang, Paul S Mischel, Sihan Wu, Zhijian J Chen. bioRxiv. - 2025 Articles
Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy.
Zeyu Chen, Ziang Zhu, Taidou Hu, Chen Yao, Tuoqi Wu. Cellular & Molecular Immunology.Alternating magnetic fields enhance anti-biofilm activity across pathogen and antibiotic space.
Miranda Hairgrove, Sneha Banerjee, Madhab Sapkota, Gerald Kramer, Varun Sadaphal, Bibin Prasad, Rajiv Chopra, David E Greenberg. Scientific Reports.The CCC complex directs phagosomal maturation and bactericidal activity in macrophages through PI(3)P regulation.
Hannes Buck, Rodrigo Pereyria, Amika Singla, Qi Liu, Daniel A Kramer, Wan-Ru Lee, Wesley Burford, Jianyi Yin, Shuai Tan, Baoyu Chen, Luis Sifuentes-Dominguez, Neal Alto, Jen Liou, Ezra Burstein. bioRxiv.Structural insights into GM4951 as a lipid droplet GTPase regulating hepatic lipid metabolism.
Rishi Raj, Yiao Jiang, Rahul Kumar Jha, Eva Marie Y Moresco, Himanshu Joshi, Zhao Zhang, Bruce Beutler. Nature Communications.Unusual inheritance of a functional cki homolog in the human pathogen Schistosoma mansoni.
George R Wendt, James J Collins. Science Advances.B-1 cells contribute to increased total IgM and shape IgG autoreactivity profiles in Lyn-/- mice but are not a major source of lupus-associated pathogenic autoantibodies.
Kristina Ottens, Anne B Satterthwaite. Frontiers in Immunology.Something from nothing: The birth of new phage defense genes.
Kevin J Forsberg. Proceedings of the National Academy of Sciences of the United States of America.HDL dysfunction: a role in the pathogenesis of cardiometabolic syndrome in chronic HIV infection?
Konstantinos Markakis, Leila Fotooh Abadi, Arnaud Kombe Kombe, Martinos Christodoulides, Theodoros Kelesidis. Metabolism: Clinical and Experimental.Moving personalized medicine from treatment to prevention - a paradigm shift in genetic conditions.
Raksha Jain. Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society.Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis.
Jake N Lichterman, Tarun Srinivasan, Ruheng Wang, Chaitanya Dende, Christina Zarek, Josue I Ramirez, Noheon Park, Hesuiyuan Wang, Wenling Li, Jiwoong Kim, Laura Coughlin, Nicole Poulides, Parastoo Sabaeifard, Suzette N Palmer, Aidan C Morrill, Brian Hassell, John M Shelton, Xin V Li, Bret M Evers, Xiaowei Zhan, Joseph S Takahashi, Lora V Hooper, Andrew Y Koh. bioRxiv.Scaffold vaccination for prevention of orthopedic device infection.
Alexander M Tatara, Shanda Lightbown, Shawn Kang, Wei-Hung Jung, Hamza Ijaz, Jean C Lee, Sandra B Nelson, Michael Super, David J Mooney. Proceedings of the National Academy of Sciences of the United States of America.The systemic effects of 22q11.2 deletion syndrome on immunity.
Nicolai S C van Oers, Kathleen E Sullivan. Journal of Human Immunity.Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon.
Kun Yang, Miranda Dunn, Gustavo Torres-Ramirez, Nicole Dobbs, Vikram G Shakkottai, Nan Yan. Cell Reports.Airflow Determines Natural Airborne Transmission of Tuberculosis in a Guinea Pig Model.
Kubra F Naqvi, Yuhui Guo, Deepak Sapkota, Pei Lu, Shibo Wang, Beatriz R S Dias, Victoria A Ektnitphong, Arabella E Martin, Bret M Evers, Lenette L Lu, Hui Ouyang, Lydia Bourouiba, Michael U Shiloh. bioRxiv.Genetic haplotypes in VWA8, OSBPL6, and ADAMTS9-AS2 are associated with immune-related adverse effects in ICI-treated patients with cancer.
Prithvi Raj, Jialiang Liu, Chengsong Zhu, Carlos Arana, Farjana J Fattah, Hong Mu-Mosley, Benjamin Switzer, Jason Y Park, Mitchell S von Itzstein, Edward K Wakeland, Igor Puzanov, Yousef Zakharia, Gregory A Daniels, Montaser F Shaheen, Yang Xie, Jeffrey A SoRelle, David E Gerber. Journal for Immunotherapy of Cancer.Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of Malaria.
Suraksha Gahalawat, Sneha Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Zhe Chen, Aloysus Lawong, David M Shackleford, Kasiram Katneni, Gong Chen, Peng Li, Alice Ng, Longjin Zhong, Meiyu Hu, Mitchell McInerney, Wen Wang, Jessica Saunders, Daniel Collins, Jaya Jayaseelan, Cassandra L Noack, Bikash C Maity, Nirupam De, Benoît Laleu, Simon F Campbell, Margaret A Phillips, Susan A Charman, Joseph M Ready. Journal of Medicinal Chemistry.Erratum to "Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells". [Mucosal Immunol. 18(5) (2025) 1199-1217].
Samuel Alvarez-Arguedas, Khadijah Mazhar, Andi Wangzhou, Ishwarya Sankaranarayanan, Gabriela Gaona, John T Lafin, Ron B Mitchell, Theodore J Price, Michael U Shiloh. Mucosal Immunology.Editorial: Gut and circulating microbiota in the pathophysiology and clinical complications of diabetes.
Dinakaran Vasudevan, Velmurugan Ganesan, Chaitanya Dende, Chethan Sampath. Frontiers in Clinical Diabetes and Healthcare.STING: a multifaced player in cellular homeostasis.
Kun Song, Lyu Heng, Nan Yan. Human Molecular Genetics.A subclass of small RNAs is encoded by exons of protein-coding genes.
Tyron Chang, Dustin C Hancks. BMC Genomics.A Campylobacter jejuni sensor phosphatase-driven two-component system integrates metabolic phosphodonors as cues in signal transduction.
Nestor Ruiz, David R Hendrixson. Proceedings of the National Academy of Sciences of the United States of America.Antisense phosphorodiamidate morpholino oligomers retain activity in Burkholderia cepacia complex biofilm.
Antonio R Mendez, Christine Pybus, David E Greenberg. Frontiers in Microbiology.Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors.
Matthew E Campbell, Sonja Stutzman, Sharon Primeaux, Deseray Sida, Minjae Lee, Avanthi T Shah, Arhanti Sadanand, Elizabeth Sokol, Natalie B Collins, Brian Turpin, Shoba Navai, Katie Albert, Theodore W Laetsch, Dinesh Rakheja, Kenneth S Chen, David E Gerber, Andrew Y Koh. Pediatric Blood & Cancer.Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na+ Pump (PfATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening.
Arturo Casas, Leah S Imlay, Vandana Thathy, Kate J Fairhurst, Adele M Lehane, Aloysus K Lawong, Ioanna Deni, Josefine Striepen, Seungheon Lee, Ashwani Kumar, Chao Xing, Hanspeter Niederstrasser, Bruce A Posner, Benoît Laleu, Susan A Charman, David A Fidock, Joseph M Ready, Margaret A Phillips. ACS Infectious Diseases.Single-cell analysis of genetically minimized Salmonella reveals effector gene cooperation in vivo.
Wesley B Burford, Hrag Dilabazian, Laura T Alto, Duo Ma, Angela B Mobley, Arun Radhakrishnan, J David Farrar, Neal M Alto. Nature Microbiology.A genome-scale drug discovery pipeline uncovers therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni.
Dylon R Stephens, Ho Yee Joyce Fung, Yan Han, Jue Liang, Zhe Chen, Joseph Ready, James J Collins. Proceedings of the National Academy of Sciences of the United States of America.A single amino acid mutation in norovirus NS4 promotes viral spread.
Mridula Annaswamy Srinivas, Robert C Orchard. bioRxiv.Identification of divergent Toxoplasma Nuclear Pore Complex components highlights speciation of mRNA export machinery.
Pravin S Dewangan, Shannon R Dohr, Jackson Trotter, Michael L Reese. bioRxiv.FliO is an evolutionarily conserved yet diversified core component of the bacterial flagellar type III secretion system.
Ekaterina P Andrianova, Amanda L Dobbins, Marc Erhardt, David R Hendrixson, Igor B Zhulin. Proceedings of the National Academy of Sciences of the United States of America.A simple, low-cost, and highly efficient protocol for rapid isolation of pathogenic bacteria from human blood.
Fatma S Coskun, Joshua Quick, Erdal Toprak. Frontiers in Microbiology.A critical role for Vibrio parahaemolyticus LPS to mediate evasion of host immune response during infection.
Jananee Jaishankar, Hyojik Yang, Ian P O'Keefe, Brandon M Tenaglia, Lisa N Kinch, Robert K Ernst, Kim Orth. Proceedings of the National Academy of Sciences of the United States of America.Translational control of innate barrier defense by the gut microbiota.
Yun Li, Runrun Wu, Xianda Ma, Jianglin Zhang, Junjie Ma, Yiran Duan, Brian Hassell, Kelly A Ruhn, Cassie L Behrendt, Chaitanya Dende, Li Wang, Andrew Lemoff, Prithvi Raj, Zheng Kuang, Lora V Hooper. bioRxiv.The β2-adrenergic receptor (Adrb2) entrains circadian gene oscillation and CD8+ T cell differentiation in response to virus infection.
Drashya Sharma, Kira A Kohlbach, Robert Maples, J David Farrar. Science Advances.Immunoengineering: An Emerging Field in Infectious Diseases.
Alexander M Tatara, Antonios G Mikos, Dimitrios P Kontoyiannis. The Journal of Infectious Diseases.Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes.
Luis Rodriguez-Rodriguez, James Pfister, Liam Schuck, Arabella E Martin, Luis M Mercado-Santiago, Vincent S Tagliabracci, Kevin J Forsberg. Cell Host & Microbe.Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells.
Samuel Alvarez-Arguedas, Khadijah Mazhar, Andi Wangzhou, Ishwarya Sankaranarayanan, Gabriela Gaona, John T Lafin, Ron B Mitchell, Theodore J Price, Michael U Shiloh. Mucosal Immunology.A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency.
Elisa B Lin, Steve Meregini, Zhao Zhang, Avishek Roy, Tandav Argula, James M Mitchell, William J Israelsen, Sara Ludwig, Jamie Russell, Jiexia Quan, Sara Hildebrand, Evan Nair-Gill, Bruce Beutler, Jeffrey A SoRelle. JCI Insight.The Rab32-LRMDA-Retriever Complex is a Key Regulator of Intestinal Immune Homeostasis.
Ran Song, Chigozie Ngoka, Amika Singla, Daniel A Kramer, Alka Diwaker, Daniel J Boesch, Qi Liu, James J Moresco, Bruce Beutler, Hans-Christian Reinecker, Ezra Burstein, Baoyu Chen, Emre E Turer. bioRxiv.Implant Infectious Diseases: An Introduction to Biomaterials for ID Physicians.
Lauren E Kemp, Alexander M Tatara. Open Forum Infectious Diseases.Higher-order epistasis drives evolutionary unpredictability toward novel antibiotic resistance.
Ilona Kamila Gaszek, Muhammed Sadik Yildiz, Devin Meng, Jose Alberto de la Paz, Sophia Maria Alvarez, Faruck Morcos, Milo Lin, Erdal Toprak. bioRxiv.The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency.
Kun Yang, Gustavo Torres-Ramirez, Nicole Dobbs, Jie Han, Makoto Asahina, Reiko Fujinawa, Kun Song, Yun Liu, Weichun Lin, Angelica Oviedo, Chuo Chen, Lei Zhu, William F Mueller, Kevin Lee, Tadashi Suzuki, Nan Yan. The Journal of Experimental Medicine.The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint.
Juliana N Flaherty, Enakshi Sivasudhan, Matthew Tegowski, Zheng Xing, Madeline M McGinnis, Olga V Hunter, Kyah M Featherston, Komal Sethia, Benjamin P Tu, Kate D Meyer, Nicholas K Conrad. Cell Reports.Prevalence and species diversity of non-tuberculous mycobacteria in North Texas.
Manoj K Sah, Lenin Mahimainathan, Muluye Mesfin, Andrew E Clark, Jeffrey A SoRelle. Journal of Infection and Public Health.Structural mechanism of DDX39B regulation by human TREX-2 and a related complex in mRNP remodeling.
Bradley P Clarke, Shengyan Gao, Menghan Mei, Dongqi Xie, Alexia E Angelos, Ashley Vazhavilla, Pate S Hill, Tolga Cagatay, Kimberly Batten, Jerry W Shay, Yihu Xie, Beatriz M A Fontoura, Yi Ren. Nature Communications.Egress-enhancing mutation reveals the inefficiency of non-enveloped virus cell exit.
Valerie J Rodriguez-Irizarry, Robert W Maples, Julie K Pfeiffer. PLOS Biology.Cutaneous Hormone Sampling and Analysis for Dermatologic Research.
Camille I Sturges, Shivani Jain, Mauricio Velasquez, Hanna Gedamu, Jessica Komarovsky, Jeffrey McDonald, Tamia Harris-Tryon. The Journal of Investigative Dermatology.Informed clinical decisions by outfoxing human FOXN1 variants.
Christian A Wysocki, Nicolai S C van Oers. The Journal of Allergy and Clinical Immunology.P. aeruginosa rhamnolipids stabilize human rhinovirus 14 virions.
Joshua J Baty, Aidan K Drozdick, Julie K Pfeiffer. bioRxiv.Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines.
Fatma Neslihan Kalkan, Muhammed Sadik Yildiz, N Ezgi Wood, Michael Farid, Melissa McCoy, Milo M Lin, Chengcheng Zhang, Bruce A Posner, Stephen S Chung, Erdal Toprak. Scientific Reports.The HP1 box of KAP1 organizes HP1α for silencing of endogenous retroviral elements in embryonic stem cells.
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