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UTSW study recommends screening for suspected obstructive sleep apnea in underweight children

Sleen apnea

DALLAS – Jan. 07, 2022 – Researchers at UT Southwestern Medical Center studied obstructive sleep apnea in a large group of children and concluded that underweight children with this condition are more likely to have decreased height, tonsillar hypertrophy, and allergic rhinitis. Screening these children for suspected obstructive sleep apnea (OSA) could be highly effective, say the researchers.

Ron Mitchell, M.D., Professor of Otolaryngology, Chief of Pediatric Otolaryngology

“We recommend nocturnal polysomnography for suspected OSA in symptomatic underweight children in order to provide timely diagnosis and treatment, especially in those children with a history of large tonsils and/or allergies,” said Ron Mitchell, M.D., Professor and Vice Chairman in the Department of Otolaryngology. Polysomnography is a comprehensive test measuring brain waves, oxygen levels, heart rate, and breathing that is used to diagnose sleep disorders. 

Dr. Mitchell is also Chief of Pediatric Otolaryngology who practices at Children’s Medical Center in Dallas. The study is published by Otolaryngology–Head and Neck Surgery.

In this study, underweight children who had a PSG for suspected OSA had a mean age of 6.4 years, and 75% were Hispanic or Black. Over 50% of them had at least 2 comorbidities, with allergies and neurologic abnormalities being the most common. Overall, the demographic and clinical characteristics between underweight children with and without OSA were similar. Height was negatively correlated with OSA, while tonsillar hypertrophy and allergies were predictors of OSA. No predictors of severe OSA were identified in this population. 

Dr. Mitchell is a leading clinician and researcher in pediatric airway conditions who has devoted much of his career to untangling the intertwined problems of OSA, large tonsils, and obesity. He studies how surgery for OSA affects kids’ behavior, sleep, health, and quality of life. Dr. Mitchell is the current President of the American Society of Pediatric Otolaryngology (ASPO),  and is the chair of multiple committees including a recent task force of the American Academy of Otolaryngology-Head and Neck Surgery that published Clinical Practice Guideline: Tonsillectomy in Children.

Additional UT Southwestern researchers involved include Courtney Johnson, Taylor Leavitt , and Romaine F. Johnson.

Dr. Mitchell holds the William Beckner, M.D., Distinguished Chair in Otolaryngology.

About UT Southwestern Medical Center

UT Southwestern, one of the nation’s premier academic medical centers, integrates pioneering biomedical research with exceptional clinical care and education. The institution’s faculty has received six Nobel Prizes and includes 25 members of the National Academy of Sciences, 16 members of the National Academy of Medicine, and 14 Howard Hughes Medical Institute Investigators. The full-time faculty of more than 2,800 is responsible for groundbreaking medical advances and is committed to translating science-driven research quickly to new clinical treatments. UT Southwestern physicians provide care in about 80 specialties to more than 117,000 hospitalized patients, more than 360,000 emergency room cases, and oversee nearly 3 million outpatient visits a year.