Clinical Trials Network Big S/W Node

Best Care Research

As a key leader in the field of mood disorders, Dr. Madhukar Trivedi serves as the Principal Investigator of the National Institute on Drug Abuse (NIDA) sponsored Clinical Trials Network (CTN) Big South/West Node that researches novel interventions aimed at improving outcomes for substance use disorders.

 

Why This Research is Important

Substance use, particularly the use of stimulants and opioids in the fourth wave of the opioid epidemic, are a major public health problem. Research is needed to develop new substance use disorder treatments and to determine how to best broadly disseminate the treatments that are currently available and effective. 

Follow our activities, find resources for providers, and general information by visiting our website here.

 

Our Studies

Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (MBC4OUD)

Learn more about this study here.

Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone:Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (SWIFT)

Learn more about this study here.

rTMS for Stimulant Use Disorders (STIMULUS)

Learn more about this study here.

Randomized, Placebo-Controlled Trial of Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)

Learn more about this study here.

Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Disorders (I-DREM)

Learn more about this study here.

Randomized, Double-blind, Placebo-controlled Trial of Monthly Injectable Buprenorphine for Methamphetamine Use Disorder (MURB)

Learn more about this study here.

Remote Methadone Ingestion Surveillance Trial (RMIST)

Learn more about this study here.

To learn more about our active research studies, visit current studies

 

Stay Engaged

 

For information about CDRC programs, research, or activities, contact us at CDRC@UTSouthwestern.edu