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10 to 70% methanol in 50 mM KH2PO4 over 25 min, 10 ml/min, monitor at 380 nm). Next, the HPLC- purified mixture was desalted on the same column (methanol was removed on a rotary evaporator, and the sample loaded in H2O and eluted with 90% methanol) and lyophilized, yielding the purified Nvoc-aa-S-CoA (40 to 80% yield) as a yellow solid. For preparation of the deprotected aa-S-CoAs, the solution of Nvoc-aa-S-CoA collected from the HPLC purification was directly photolysed (4°C, 350 nm, 1 hour

The Cancer Cell Imaging Core (CCIC) at UT Southwestern enables researchers to visualize cancer processes with unprecedented resolution and throughput. CCIC combines state-of-the-art multiscale imaging, tissue clearing, thick-tissue cyclic immunofluorescence, expansion microscopy, and tailored image

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Skip to main content News August, 2021 Npas4 gene may be a master timekeeper for the brain’s circadian clock May 2019 Dr. Joseph Takahashi receives $500,000 Gruber Neuroscience prize UTSW Newsroom Gruber prize article

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Michaely Lab teaching

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The Structural Biology Lab (SBL) provides access and assistance with the techniques of X-ray crystallography, small angle X-ray scattering and high-resolution imaging as well as single particle reconstruction in cryo-electron microscopy.

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