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Autophagosome: Lysosome fusion | Yin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yin-lab/yin-helen-lab/research/autophagosome-lysosome-fusion
GABARAP recruits PI4KIIα to autophagosomes. Depletion of either GABARAP or PI4KIIα by siRNA, or overexpression of the dominant negative kinase-dead PI4KIIα, blocks autophagic flux by inhibiting autophagosome fusion with lysosomes to generate grossly enlarged autophagosomes.
Teaching | Michaely Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/michaely-lab/teaching
Michaely Lab teaching
People | Zhong Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/zhong-lab/people
Meet the Zhong Lab team.
People | Chung Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/chung-lab/people
Meet the Chung Lab team
Contact Us | Wetzel Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/wetzel-lab/contact-us
Contact the Wetzel Lab.
People | Mootha Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/mootha-lab/people
Meet the Mootha Lab team.
Research | Wetzel Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/wetzel-lab/research
Learn about Wetzel Lab's research.
Metabolic Hallmarks of Cancer | Corbin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/corbin-lab/research/metabolic-hallmarks-cancer
Metabolic reprogramming is now firmly established as a hallmark of cancer
About Us | Engelking Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/engelking-lab/about-us
About Engelking Lab
Lipid Reprogramming | Corbin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/corbin-lab/research/metabolic-hallmarks-cancer/lipid-reprogramming
Development and progression of cancer are frequently associated with altered rates of lipid synthesis, mobilization and metabolism in tumor cells.