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Skip to main content Pan Lab in the News Duojia Pan elected to National Academy of Sciences (2023) YAP/TAZ harness the power of polyamines (2022) Duojia Pan joins JCC Board of Scientific Advisors (2020) Duojia Pan returns to UT Southwestern (2016) Hippo signaling in anti-bacterial defense (2016) Duojia Pan awarded the Paul Marks Prize for Innovation in Cancer Research (2013) Unraveling the elusive molecular function of the classic tumor suppressor NF2/Merlin (2013) Linking the classic tumor

1 updated May 2025 Sendai virus reprogrammed iPSC Lines * Clone used for CRISPR/Cas9 editing of GAA repeats Line Clone # Sex GAA repeat number in fibroblasts GAA repeat number in iPSCs Karyotype data Karyotype passage CTRL 3348 6 M Control size Control size Yes, normal p11 CTRL 7522 5 F Control size Control size Yes, normal p15 CTRL 7522 12 F Control size Control size Yes, normal p13 CTRL 6718 1 M Control size Control size Yes, normal p4 CTRL 6718 6 M

Learn about the Engelking Lab's research

RESEARCH ON SYMPTOM MONITORING AND PREVENTIVE COGNITIVE THERAPY FOR PERINATAL DEPRESSION The Department of Psychiatry at the University of Texas Southwestern Medical Center is conducting research sponsored by the National Institute of Mental Health (NIMH) on perinatal depression, aiming to develop a treatment program for conceiving or pregnant women at risk for depressive relapse and recurrence. We are recruiting women with a history of depression who are planning to become

The Postdoctoral Association helps postdocs develop a sense of community and promotes training and career development.

Meet the Engelking Lab team

1 Napierala Lab protocol for human skin fibroblast culture (May 2022) Necessary Reagents Reagent Company Catalog Number DMEM, high glucose Gibco/Life Technologies 11965-092 Fetal bovine serum Hyclone SH30910.03 MEM Non-essential amino acids (NEAA) Gibco/Life Technologies 11140-050 0.25% Trypsin-EDTA, phenol red Gibco/Life Technologies 25200-056 DPBS (1X) Gibco/Life Technologies 14190-144 Fibroblast Medium recipe: DMEM, high glucose 15% fetal bovine serum (FBS

Meet the Wetzel Lab team.

1 Sendai virus reprogrammed iPSC Lines Line Clone# Sex GAA repeat number in fibroblasts GAA repeat number in iPSCs Earliest passage Karyotype data Karyotype passage 1 CTRL 3348 6 M Control size Control size P5 Yes, normal P11 2 CTRL 7522 5 F Control size Control size P9 Yes, normal P15 3 CTRL 6718 1 M Control size Control size P2 Yes, normal P4 4 CTRL 6718 6 M Control size Control size P2 Yes, normal P4 5 CTRL 6719 1 F Control size Control size

Skip to main content GEF-H1-Dependent Regulation of Anti-Tumor Immunity We discovered that intracellular activation of the GEF-H1 signaling pathway induces immune responses and dendritic cell maturation similar to microbial pattern recognition receptors. GEF-H1 directed immunity emerges as a critical mechanism that controls dendritic cell maturation upon disruption of microtubules. This immune activation pathway is induced by microtubule destabilization and controls maturation of dendritic cells