Eugene McDermott Center for Human Growth and Development Southwestern Medical School 5323 Harry Hines Blvd. / Dallas, Texas 75390-8591 (214) 648-1695 Fax (214) 648-1666 Email: chao.xing@utsouthwestern.edu Computational Biologist I & II The Bioinformatics Lab of McDermott Center for Human Growth and Development at University of Texas Southwestern Medical Center at Dallas solicits applications for Computational Biologist I & II. Experience & Education Required 1. Master's or

Zhongzheng (Brooks) Fu, Ph.D. Last updated: September, 2023 ORCID: 0000-0002-2572-6284 Email: zhongzheng.fu@utsouthwestern.edu Website: zfu-lab.org 5323 Harry Hines Blvd, MC 8855 Dallas, TX 75390 United States Academic Positions 2023 – on Assistant Professor Department of Neurological Surgery UT Southwestern Medical Center Dallas, TX, USA 2023 – on Visiting Scholar Division of the Humanities and Social Sciences California Institute of Technology Pasadena, CA, USA Postdoctoral Trainings

Eugene McDermott Center for Human Growth and Development Southwestern Medical School 5323 Harry Hines Blvd. / Dallas, Texas 75390-8591 (214) 648-1695 Fax (214) 648-1666 Email: chao.xing@utsouthwestern.edu Postdoctoral Fellowship in Statistical Genomics & Genetics The Bioinformatics Lab of McDermott Center for Human Growth and Development at University of Texas Southwestern Medical Center at Dallas solicits applications for postdoctoral fellowship in statistical genomics

Single Cell Transcriptomics – a simple walkthrough Adwait Sathe, PhD McDermott Center Bioinformatics Lab adwait.sathe@utsouthwestern.edu MCDERMOTT CENTER BIOINFORMATICS LAB 1 mailto:Adwait.sathe@utsouthwestern.edu RNASeq RNASeq 2 MCDERMOTT CENTER BIOINFORMATICS LAB https://www.10xgenomics.com/solutions/single-cell/ Single cell RNA Sequencing Workflow Dissociation of solid tissue Isolate single cells DROP-Seq, Smart-Seq etc. RNA cDNA Amplified RNA Amplified cDNA Sequencing

Jiaen Liu, Ph.D. Assistant Professor, Advanced Imaging Research Center and Radiology University of Texas Southwestern Medical Center, Dallas, TX, USA Email: jiaen.liu@utsouthwestern.edu EDUCATION Ph.D. Biomedical Engineering, University of Minnesota, Minneapolis, MN 2015 Minor in Neuroscience, 2011 M.S. Instruments Science and Technology, Tsinghua University, Beijing, China 2007 B.S. Environmental Engineering, Tsinghua University, Beijing, China 2005 RESEARCH EXPERIENCE Assistant Professor

Ready; Catalysis Nonlinear Effects Outline Definitions Origins of nonlinear effects in enantioselective reactions ML2 model Reservoir model Transition-state model Kinetic aspects of nonlinear effects Asymmetric amplification Cool tricks Origin of biotic asymmetry? Key reviews Kagan, ACIEE, 1998, 2922 (a pretty complete review, source of many of my figures) Kagan, Advanced Syn. Cat., 2001, 227 (an overview) Blackmond, Accts, 2000, 402 (kinetic aspects) Soai

2292 J . Med. Chem. 1996,38, 2292-2301 Increasing Binding Constants of Ligands to Carbonic Anhydrase by Using “Greasy Tails” Jinming Gao, Shuang Qiao, and George M. Whitesides* Department of Chemistry, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138 Received February 13, 1995@ Two series ofpara-substituted benzenesulfonamides have been examined as inhibitors for bovine carbonic anhydrase I1 (CAII, EC 4.2.1.1). Both series have hydrophobic alkyl group R connected

1 Kinetic Resolutions Material outline: For the Scientist in you: Definitions Theoretical treatment For the technician in you: Practical considerations Useful KR’s Oxidative KR of allylic alcohols An extreme example Acylation/deacylation Hydrogenation olefins ketones Dynamic kinetic resolution Epoxide ring opening A very extreme example Parallel kinetic resolution General References: Vedejs, ACIEE, 2005, 3974 Jacobsen, Adv. Syn

Information regarding User Group D, Molecular Therapeutics of Cancer, for UT Southwestern's Cyclotron and Radiochemistry Program Adult Core.

COMMUNICATIONS Surface Modification of Polyanhydride Microspheres JINMING GAO†,‡, LAURA NIKLASON†,‡, XIAO-MEI ZHAO§, AND ROBERT LANGER*,† Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts 02114, and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138 Received July 25, 1997. Final revised manuscript received