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Kinetic Resolutions - Ready Lab - UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/sites/default/files/2022-08/kinetic-resolutions.pdf

1 Kinetic Resolutions Material outline: For the Scientist in you: Definitions Theoretical treatment For the technician in you: Practical considerations Useful KR’s Oxidative KR of allylic alcohols An extreme example Acylation/deacylation Hydrogenation olefins ketones Dynamic kinetic resolution Epoxide ring opening A very extreme example Parallel kinetic resolution General References: Vedejs, ACIEE, 2005, 3974 Jacobsen, Adv. Syn

Prolonged activation of innate immune pathways by a polyvalent STING agonist

https://labs.utsouthwestern.edu/sites/default/files/2022-08/132_Li_NBME_2021_0.pdf

Articles https://doi.org/10.1038/s41551-020-00675-9 1Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 2Department of Pathology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 3Department of Otolaryngology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 4Howard Hughes

Moral Reasoining in Scientific Research

https://labs.utsouthwestern.edu/sites/default/files/2022-07/Moral_Reasong_in_Scific_Res.pdf

Moral Reasoning in Scientific Research Cases for Teaching and Assessment Developed by Muriel J. Bebeau, University of Minnesota with Kenneth D. Pimple, Karen M. T. Muskavitch, Sandra L. Borden, and David H. Smith, Indiana University December 1995 These materials were developed for a project entitled “Teaching Research Ethics: A Workshop at Indiana University” (TRE). Funding was provided by the United States Department of Education’s Fund for the Improvement of Postsecondary Education

molecular-mechanisms-kraus.pdf

https://labs.utsouthwestern.edu/sites/default/files/2024-01/molecular-mechanisms-kraus.pdf

Postdoctoral Training in Gene Regulation Molecular Mechanisms, Computational Genomics, Mouse Genetic Models, RNA Biology and Noncoding RNAs, Protein Structure, Translational/Clinical A postdoctoral training position is available in the laboratory of Dr. W. Lee Kraus, in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center to study signaling and gene regulation. The Kraus Lab has several exciting projects related to a broad array of

bioinformatics-comp-bio-genomics-of-gene-regulation-kraus.pdf

https://labs.utsouthwestern.edu/sites/default/files/2024-01/bioinformatics-comp-bio-genomics-of-gene-regulation-kraus.pdf

Postdoctoral Training in Bioinformatics and Computational Biology Studies on the Genomics of Gene Regulation A postdoctoral training position is available in the laboratory of Dr. W. Lee Kraus, in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center to study gene regulation on a global scale. The Kraus lab has many exciting, ongoing projects related to the genomics of signal-regulated gene expression in various biological models

structural-biology-and-biochemistry-gene-regulation-kraus-liu.pdf

https://labs.utsouthwestern.edu/sites/default/files/2024-01/structural-biology-and-biochemistry-gene-regulation-kraus-liu.pdf

Structural Biology and Biochemistry of Gene Regulation A joint postdoctoral training position is available in the laboratories of Dr. W. Lee Kraus and Dr. Xin Liu in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center to study signaling and gene regulation and molecular biophysics of gene regulation. We are seeking a trainee interested in studying gene regulatory complexes, who will initiate and execute research projects

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource

https://labs.utsouthwestern.edu/sites/default/files/2023-07/Data%20Science%20Fellowship%20Agreement.pdf

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science Fellowship Agreement SCCC-DSSR This agreement is between the parties named below and the Director of SCCC-DSSR, Professor Jeon Lee. By signing this document, awardees (and their mentors, if applicable) acknowledge and agree to abide by the fellowship conditions listed below. Fellowship Awardee (Full Name

signaling-gene-reg-using-proteomics-mass-spec-kraus.pdf

https://labs.utsouthwestern.edu/sites/default/files/2024-01/signaling-gene-reg-using-proteomics-mass-spec-kraus.pdf

Postdoctoral Training in Signaling and Gene Regulation using Proteomics and Mass Spectroscopy Dr. W. Lee Kraus is currently seeking applicants with a Ph.D. degree and significant experience in mass spectroscopy for postdoctoral training in the Laboratory of Signaling and Gene Regulation within the Cecil H. and Ida Green Center for Reproductive Biology Sciences. The research in the Kraus lab covers a broad array of topics, including signaling, gene regulation, and genome function

CV_May 2022

https://labs.utsouthwestern.edu/sites/default/files/2022-06/debrabander-cv-website.pdf

CURRICULUM VITAE Jef Karel De Brabander, Ph.D. Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX-75390-9038 Voice: (214) 648-7808, Fax: (214) 648-0320, E-mail: jef.debrabander@utsouthwestern.edu Education December 1993 Ph.D. in Chemistry (Highest Honors), University of Gent, Belgium July 1987 B.Sc. in Chemistry (Distinction), University of Gent, Belgium Professional Experience 2011- Julie and Louis

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles

https://labs.utsouthwestern.edu/sites/default/files/2022-08/129_Li_ACR_2020-min.pdf

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles Published as part of the Accounts of Chemical Research special issue “Chemistry in Cancer Immunotheranostics”. Suxin Li, Zachary T. Bennett, Baran D. Sumer, and Jinming Gao* Cite This: Acc. Chem. Res. 2020, 53, 2546−2557 Read Online ACCESS Metrics & More Article Recommendations CONSPECTUS: Immunotherapy has transformed the field of oncology and patient care. By leveraging the