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1310 IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 21, NO. 10, OCTOBER 2002 X-Ray Computed Tomography Methods forIn Vivo Evaluation of Local Drug Release Systems Kyle A. Salem, Student Member, IEEE, Agata Szymanski-Exner, Roee S. Lazebnik, Michael S. Breen, Jinming Gao, and David L. Wilson�, Member, IEEE Abstract—Recent advances in drug delivery techniques have necessitated the development of tools forin vivomonitoring of drug distributions. Gamma emission imaging and magnetic resonance imaging

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Journal of Controlled Release 91 (2003) 157–166 www.elsevier.com/ locate/ jconrel Q uantification of in vivo doxorubicin transport from PLGA millirods in thermoablated rat livers a ,1 b a a a ,*Feng Qian , Nicholas Stowe , Erin H. Liu , Gerald M. Saidel , Jinming Gao aDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106,USA bDepartment of Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106,USA Received 31 October 2002

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