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The Hamon Center for Regenerative Science & Medicine awards fellowships to talented graduate student or postdoctoral trainees at UT Southwestern.

Competition between Blown Fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo Peng Jin1,*, Rui Duan1,*, Fengbao Luo1, Guofeng Zhang2, Sabrina N. Hong1, and Elizabeth H. Chen1,3 1 Dept. of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2 Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institute of Health, Bethesda, MD

Towards a molecular pathway for myoblast fusion in Drosophila Elizabeth H. Chen1,2 and Eric N. Olson1 1Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA 2Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA Intercellular fusion among myoblasts is required for the generation of multinucleated muscle fibers during

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JCB: Article The Rockefeller University Press   $30.00 J. Cell Biol. Vol. 191 No. 5  1013–1027 www.jcb.org/cgi/doi/10.1083/jcb.201006006 JCB 1013 K.L. Sens and S. Zhang contributed equally to this paper. P. Jin and R. Duan contributed equally to this paper. Correspondence to Elizabeth H. Chen: echen@jhmi.edu Abbreviations used in this paper: Ants, Antisocial; Duf, Dumbfounded; FCM, fusion-competent myoblast; HPF/FS, high pressure freezing/freeze substitution; MMD, multiple membrane

1 updated May 2025 Sendai virus reprogrammed iPSC Lines * Clone used for CRISPR/Cas9 editing of GAA repeats Line Clone # Sex GAA repeat number in fibroblasts GAA repeat number in iPSCs Karyotype data Karyotype passage CTRL 3348 6 M Control size Control size Yes, normal p11 CTRL 7522 5 F Control size Control size Yes, normal p15 CTRL 7522 12 F Control size Control size Yes, normal p13 CTRL 6718 1 M Control size Control size Yes, normal p4 CTRL 6718 6 M

Mitral Valve Phase Contrast Imaging Is a More Reproducible Method of Determining Cardiac Rest Periods for Whole-Heart Coronary Magnetic Resonance Angiography in Congenital Heart Disease than 4 Chamber Cine. Maria Batsis, MD; F. Gerald Greil, MD, PhD; Animesh Tandon, MD, MS; Tarique Hussain, MD, PhD University of Texas Southwestern Medical Center, Dallas, TX, USA; Children’s Medical Center of Dallas Background Whole heart coronary magnetic resonance angiography (CMRA) offers detailed

Cell, Vol. 114, 751–762, September 19, 2003, Copyright 2003 by Cell Press Control of Myoblast Fusion by a Guanine Nucleotide Exchange Factor, Loner, and Its Effector ARF6 regulators of myoblast fusion identified genetically in Drosophila are likely to provide insights into mammalian myogenesis, as well as intercellular fusion in general. The somatic musculature of the Drosophila embryo is derived from the embryonic mesoderm. During mid- Elizabeth H. Chen, Brian A. Pryce, Jarvis A. Tzeng

1 updated May 2025 Napierala Lab protocol for culturing human iPSCs For additional details and recommendations, please refer to “Maintenance of Human Pluripotent Stem Cells in mTeSRTM Plus” Technical Manual (STEMCELL Technologies). Necessary Reagents Reagent Company Catalog Number Corning™ Matrigel™ hESC-Qualified Matrix Fisher Scientific 08-774-552 mTeSRTM Plus Complete Kit STEMCELL Technologies 100-0276 CryoStor® CS10 STEMCELL Technologies 07930 Dispase 1U/mL, 100mL