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JOURNAL OF CELLULAR PHYSIOLOGY 209:604–610 (2006) Mornings With Art, Lessons Learned: Feedback Regulation, Restriction Threshold Biology, and Redundancy Govern Molecular Stress Responses ERIK A. BEY, SHELLY M. WUERZBERGER-DAVIS, JOHN J. PINK, CHIN-RANG YANG, SHINAKO ARAKI, KATHRYN E. REINICKE, MELISSA S. BENTLE, YING DONG, EVA CATALDO, TRACY L. CRISWELL, MARK W. WAGNER, LONGSHAN LI, JINMING GAO, AND DAVID A. BOOTHMAN* Laboratory of Molecular Stress Responses, Department of Pharmacology and

Modulating b-Lapachone Release from Polymer Millirods through Cyclodextrin Complexation FANGJING WANG,1 ELVIN BLANCO,2 HUA AI,3 DAVID A. BOOTHMAN,2 JINMING GAO2 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207 2Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-8590 3National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China Received 3 March 2006

Antitumor efficacy and local distribution of doxorubicin via intratumoral delivery from polymer millirods Brent D. Weinberg,1 Hua Ai,2 Elvin Blanco,3 James M. Anderson,4 Jinming Gao3 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China 3Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 4Institute of Pathology

Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems Norased Nasongkla, † Erik Bey, † Jimin Ren, ‡ Hua Ai, † Chalermchai Khemtong, † Jagadeesh Setti Guthi, † Shook-Fong Chin, † A. Dean Sherry, ‡ David A. Boothman, † and Jinming Gao* ,† Simmons ComprehensiVe Cancer Center, UniVersity of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines BouleVard, Dallas, Texas 75390, and AdVanced Imaging Research Center, UniVersity of Texas Southwestern

119 (2007) 111–120 www.elsevier.com/locate/jconrel Journal of Controlled Release A mechanistic model of controlled drug release from polymer millirods: Effects of excipients and complex binding Fangjing Wang a, Gerald M. Saidel a,⁎, Jinming Gao b a Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106–7207, United States b Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390–8590, United States

Noninvasive Monitoring of Local Drug Release Using X-ray Computed Tomography: Optimization and In Vitro/In Vivo Validation AGATA SZYMANSKI-EXNER,1 NICHOLAS T. STOWE,2 KYLE SALEM,1 ROEE LAZEBNIK,1 JOHN R. HAAGA,3 DAVID L. WILSON,1 JINMING GAO1,3 1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 2Department of Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 3Department of Radiology, University

J O U R N A L O F M A T E R I A L S S C I E N C E 3 9 (2 0 0 4 ) 1429 – 1432 Size-controlled polyelectrolyte nanocapsules via layer-by-layer self-assembly H. AI , J . GAO Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106 E-mail: jinming@cwru.edu Nanomaterials have found many important applica- tions in biomedical, pharmaceutical, electronic, and molecular diagnostic fields. The recent introduction of electrostatic layer-by-layer (LbL) self-assembly

Biorepository: Multi-Specimen Biobank Access Our biorepository provides access to a diverse collection of biological specimens, including blood, plasma, serum, and tissue samples. This multi-specimen biobank supports a wide range of research projects, ensuring the availability of high-quality samples for future studies. Our extensive biorepository offers numerous advantages for clinical research. It enhances research capabilities by providing a diverse array of biological samples, which are

Effect of fibrous capsule formation on doxorubicin distribution in radiofrequency ablated rat livers Elvin Blanco,1 Feng Qian,1 Brent Weinberg,1 Nicholas Stowe,2 James M. Anderson,3 Jinming Gao1 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2Department of Surgery, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 3Institute of Pathology, University Hospitals of Cleveland, Cleveland, Ohio 44106 Received 24 October 2003