Data acquired on the NMR Core spectrometers can be instantly and easily accessed remotely on the facility’s samba server via network drives.

Chart of instruments and rates for Nuclear Magnetic Resonance Core - UT Southwestern

Helpful documents and instructions for working with the Nuclear Magnetic Resonance Core facility at UT Southwestern.

The Biochemistry NMR Core is a 24/7, open access facility where, after receiving the required training, users generally operate the instruments themselves and run their own samples. However, services are also available to UTSW internal users who prefer to have their samples run for them by facility

The IRB review process includes a pre-review by an IRB analyst as well as IRB, exempt, and expedited and full-board reviews.

Publications Recent publications (core staff in bold) Wang W, Ranjan A, Zhang W, Liang Q, MacMillan KS, Chapman K, Wang X , Chandrasekaran P, Williams NS , Rosenbaum DM, De Brabander JK. Novel orexin receptor agonists based on arene- or pyridine-fused 1,3-dihydro-2H-imidazole-2-imines. Bioorg Med Chem Lett . 2024 Feb 1; 99 : 129624 . PubMed PMID: 38272190 . Prakasam G, Mishra A, Christie A, Miyata J, Carrillo D, Tcheuyap VT, Ye H, Do QN, Wang Y, Reig Torras O, Butti R, Zhong H, Gagan J, Jones KB

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

The Electron Microscopy Core Facility (EMCF) offers TEM of cells & tissues, negative staining, whole-mount SEM, correlative LM and EM, and Immunogold labeling.

Photo Gallery Click image to view full version - Rendering of frontal mouse brain section Mouse brain; frontal sectioning. 3-color dataset was acquired on Zeiss LSM980 with AiryScan2 and AI sample finder; Objective: Plan-Apochromat 25x/0.8 oil immersion. Top: Overview. Right side: raw data, Middle: raw data + overlay; Left: overlay - Imaris spot detection for red/blue channels and surface detection for green channel. Bottom: zoom-in. Image properties: 735 stitched tiles; pixel size: 0.124 x

Sequencing Our facility is equipped with one Illumina NextSeq 2000, three NextSeq 500s, and one Miseq System. The NextSeq 2000 offers three flowcells: Flowcell # of reads Read Lengths P1 100 M 300 Cycles P2 400 M 100, 200 and 300 Cycles P3 1.2 B 50, 100, 200 and 300 Cycles The NextSeq 500 offers 5 flowcells: Flowcell # of reads Kit Capacity 75 High Output 400 M 75 Cycles 150 Mid Output 130 M 150 Cycles 150 High Output 400 M 150 Cycles 300 Mid Output 130 M 300 Cycles 300 High Output 400 M 300