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A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or “jumping genes,” from hopping around the human genome.

Two UT Southwestern Medical Center researchers – a biochemist and a molecular biologist – are among 33 distinguished scientists nationwide named Howard Hughes Medical Institute (HHMI) Investigators.

Members of UT Southwestern Medical School’s Class of 2025 gathered with anticipation inside the Bryan Williams, M.D., Student Center gymnasium Friday morning to learn where they will begin the next phase of their training as residents.

You’re eating or drinking something frozen, like a snow cone, ice cream, or ice pops – probably a bit too eagerly – and you get one of those sudden-onset, painful headaches known as “brain freeze.” Man, does it hurt, but usually not for long, and it’s not harmful, according to an expert at UT

Researchers at UT Southwestern Medical Center have identified a novel parameter of T cells that could help oncologists anticipate which patients would be most likely to develop immunotherapy toxicity.

A singer’s primary genre can impact the likelihood of developing vocal fold injury and may even influence the specific type of injury that occurs, a recent study by UT Southwestern researchers suggests.

A mutation in the gene that causes cystic fibrosis may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study by UT Southwestern researchers suggests.

An investigational therapy significantly shrank lung cancer tumors that are notoriously resistant to treatment by encouraging an attack from natural killer (NK) cells in an animal model, a study led by UT Southwestern Medical Center researchers shows.

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center’s Kidney Cancer Program sheds light.