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UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – for the sixth consecutive year and ranks among the top hospitals nationally in nine specialties ranging from brain to heart to cancer care.

– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

A targeted therapy using three different drugs significantly delayed progression and extended survival for breast cancer patients whose HER2 gene is mutated.

Read past stories about the extraordinary work being done and the passionate people behind it.

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity.

Blood pressure readings taken from neuroscience intensive care unit (NSICU) patients had marked differences between opposite sides of the body and different anatomical sites in each individual

Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body’s key cancer defenses, a new study led by UT Southwestern researchers suggests.

Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory.

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib. The finding, published in the journal Gastroenterology, may lead to alternative

Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers.