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Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife.

A targeted therapy using three different drugs significantly delayed progression and extended survival for breast cancer patients whose HER2 gene is mutated.

Read past stories about the extraordinary work being done and the passionate people behind it.

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – for the sixth consecutive year and ranks among the top hospitals nationally in nine specialties ranging from brain to heart to cancer care.

– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

Drugs that are already approved by the U.S. Food and Drug Administration (FDA) could hold promise in fighting the new infection known as coronavirus disease 2019 (COVID-19)...

Read past stories about the extraordinary work being done and the passionate people behind it.

Read past stories about the extraordinary work being done and the passionate people behind it.

Overweight and obesity patients without diabetes who switched GLP-1 receptor agonist (GLP-1RA) drugs were more likely to stick with their treatment longer than those who didn’t switch, according to a new study by UT Southwestern Medical Center researchers.

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.